{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:14:48Z","timestamp":1790651688898,"version":"4.1.0"},"reference-count":48,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2014,5,27]],"date-time":"2014-05-27T00:00:00Z","timestamp":1401148800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The epidemiology of West Nile virus (WNV) in Israel is different from other neighbouring countries in the Middle East where disease burden has been minimal. We analysed a cohort of Ashkenazi Jewish patients with symptomatic WNV infection (<jats:italic>n<\/jats:italic>\u00a0=\u00a039), and WNV-negative controls (<jats:italic>n<\/jats:italic>\u00a0=\u00a061), for nine genetic variants that has been suggested to be associated with susceptibility to WNV. Two single nucleotide polymorphisms were significantly more frequent in WNV-infected than non-infected individuals, rs7280422 (<jats:italic>MX1<\/jats:italic>) [odds ratio (OR) 4\u00b705, 95% confidence interval (CI) 2\u00b704\u20138\u00b703, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00\u00b7001] and rs3213545 (<jats:italic>OASL<\/jats:italic>) (OR 1\u00b785, 95% CI 1\u00b703\u20133\u00b73, <jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b703). Genetic polymorphism may play a significant role in susceptibility to WNV infection in Ashkenazi Jews<\/jats:p>","DOI":"10.1017\/s0950268814001290","type":"journal-article","created":{"date-parts":[[2014,5,27]],"date-time":"2014-05-27T19:04:14Z","timestamp":1401217454000},"page":"857-863","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":16,"title":["Genetic variants associated with susceptibility of Ashkenazi Jews to West Nile virus 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