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Incidence of high- and low-grade lesions in women aged \u2a7e30 years with a baseline HPV infection increased over follow-up time (5\u2013127 months), although incidence generally remained &lt;10%. Without baseline HPV infection, incidence of high-grade lesions remained low over follow-up time (&lt;5% over 5\u2013122 months). Incidence of high-grade lesions in women aged \u2a7e30 years with baseline HPV infection appeared similar to that in women aged &lt;30 years. In some women aged &lt;30 years, high-grade lesions can develop relatively shortly after initial HPV infection. We observed an increase in low-grade lesions over time in women aged \u2a7e30 years with baseline HPV infection, potentially indicative of an HPV infection that is potentially progressing to higher grade lesions.<\/jats:p>","DOI":"10.1017\/s0950268814001356","type":"journal-article","created":{"date-parts":[[2014,5,30]],"date-time":"2014-05-30T10:21:17Z","timestamp":1401445277000},"page":"225-241","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":17,"title":["Worldwide incidence of cervical lesions: a systematic review"],"prefix":"10.1017","volume":"143","author":[{"given":"J.","family":"TING","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. F.","family":"ROSITCH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. 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