{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:30:35Z","timestamp":1777552235191,"version":"3.51.4"},"reference-count":41,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2014,7,18]],"date-time":"2014-07-18T00:00:00Z","timestamp":1405641600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>This study aimed to assess and compare the epidemiology of faecal carriage of extended spectrum<jats:italic>\u03b2<\/jats:italic>-lactamase-producing enterobacteria (ESBL-E) in Hepatology departments of two hospitals specializing in liver diseases, Theodor Bilharz Research Institute (TBRI) in Cairo (Egypt) and Beaujon Hospital (Bj) in Clichy (France). CTX-M groups were identified by PCR, and TEM and SHV derivatives with the check-point system. Phylogenetic groups of<jats:italic>E. coli<\/jats:italic>were determined by multiplex PCR, and clone ST131 by PCR of gene<jats:italic>pabB<\/jats:italic>. Prevalence of ESBL-E was 77\u00b76% (45\/58) in TBRI and 6\u00b75% (13\/199) in Bj (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a010<jats:sup>\u22127<\/jats:sup>). Previous hospitalization was more common (<jats:italic>P<\/jats:italic>\u00a0=\u00a00\u00b7003) in Bj patients (93%) than in TBRI patients (45%) suggesting high prevalence of ESBL-E in the Egyptian community. The presence of<jats:italic>E. coli<\/jats:italic>B2 ST131 among ESBL-E faecal<jats:italic>E. coli<\/jats:italic>in Egypt confirms its pervasiveness in the community and raises concern regarding this highly virulent and resistant clone.<\/jats:p>","DOI":"10.1017\/s0950268814001812","type":"journal-article","created":{"date-parts":[[2014,7,18]],"date-time":"2014-07-18T13:46:58Z","timestamp":1405691218000},"page":"1247-1255","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":13,"title":["Faecal carriage of extended-spectrum<i>\u03b2<\/i>-lactamase (ESBL)-producing enterobacteria in liver disease patients from two hospitals in Egypt and France: a comparative epidemiological study"],"prefix":"10.1017","volume":"143","author":[{"given":"N. S.","family":"FAM","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"DEFASQUE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"BERT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"LEFLON-GUIBOUT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"EL-RAY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"EL-GHANNAM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. E.","family":"ATTIA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"OMAR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. G.","family":"DESOUKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"VALLA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.-H.","family":"NICOLAS-CHANOINE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2014,7,18]]},"reference":[{"key":"S0950268814001812_ref11","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.66.10.4555-4558.2000"},{"key":"S0950268814001812_ref4","doi-asserted-by":"publisher","DOI":"10.3201\/eid0908.030094"},{"key":"S0950268814001812_ref20","first-page":"285","article-title":"Faecal colonization by extended-spectrum beta-lactamase-producing Escherichia coli from hospitalized patients","volume":"19","author":"Al-Agamy","year":"2008","journal-title":"New Egyptian Journal of Microbiology"},{"key":"S0950268814001812_ref27","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.1.1-14.2004"},{"key":"S0950268814001812_ref16","doi-asserted-by":"publisher","DOI":"10.1086\/597505"},{"key":"S0950268814001812_ref33","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-9-84"},{"key":"S0950268814001812_ref15","doi-asserted-by":"publisher","DOI":"10.1038\/ajgsup.2012.3"},{"key":"S0950268814001812_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S1590-8658(01)80134-1"},{"key":"S0950268814001812_ref38","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn463"},{"key":"S0950268814001812_ref34","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1128\/IAI.67.2.546-553.1999","article-title":"The link between phylogeny and virulence in Escherichia coli extraintestinal infection","volume":"67","author":"Picard","year":"1999","journal-title":"Infection and Immunology"},{"key":"S0950268814001812_ref24","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkg101"},{"key":"S0950268814001812_ref19","doi-asserted-by":"publisher","DOI":"10.2310\/JIM.0b013e318238748e"},{"key":"S0950268814001812_ref28","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.4.657-686.2005"},{"key":"S0950268814001812_ref39","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e3283398dc1"},{"key":"S0950268814001812_ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-006-0242-8"},{"key":"S0950268814001812_ref35","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks278"},{"key":"S0950268814001812_ref1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0400456101"},{"key":"S0950268814001812_ref5","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-10-204"},{"key":"S0950268814001812_ref29","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkl483"},{"key":"S0950268814001812_ref10","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.10.3736-3742.2004"},{"key":"S0950268814001812_ref18","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks018"},{"key":"S0950268814001812_ref22","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.7.3309-3313.2005"},{"key":"S0950268814001812_ref36","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00734-08"},{"key":"S0950268814001812_ref3","first-page":"1365","article-title":"Faecal carriage of extended-spectrum \u03b2-lactamase-producing bacteria in the community","volume":"15","author":"Kader","year":"2009","journal-title":"Eastern Mediterranean Health Journal"},{"key":"S0950268814001812_ref21","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks118"},{"key":"S0950268814001812_ref31","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.ijantimicag.2006.01.007","article-title":"First description of CTX-M \u03b2-lactamase-producing clinical Escherichia coli isolates from Egypt","volume":"27","author":"Al-Agamy","year":"2006","journal-title":"International Journal of Antimicrobial Agents"},{"key":"S0950268814001812_ref26","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.10.4769-4775.2004"},{"key":"S0950268814001812_ref12","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm464"},{"key":"S0950268814001812_ref13","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkp194"},{"key":"S0950268814001812_ref17","doi-asserted-by":"publisher","DOI":"10.3109\/00365540903493715"},{"key":"S0950268814001812_ref23","doi-asserted-by":"publisher","DOI":"10.1086\/519865"},{"key":"S0950268814001812_ref37","doi-asserted-by":"publisher","DOI":"10.3201\/eid1402.070350"},{"key":"S0950268814001812_ref40","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2893.2011.01576.x"},{"key":"S0950268814001812_ref8","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2010.0063"},{"key":"S0950268814001812_ref32","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-2-76"},{"key":"S0950268814001812_ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2009.11.003"},{"key":"S0950268814001812_ref25","doi-asserted-by":"publisher","DOI":"10.3201\/eid1806.110139"},{"key":"S0950268814001812_ref14","doi-asserted-by":"publisher","DOI":"10.1086\/500936"},{"key":"S0950268814001812_ref41","unstructured":"El-Zanaty F , Way A . Hepatitis C in Egypt cited from Egypt Demographic and Health Survey 2008. Cairo, Egypt: Ministry of Health, El-Zanaty and Associates, and Macro International (www2.hawaii.edu\/~dewolfe\/Epidemic.html)."},{"key":"S0950268814001812_ref6","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23264"},{"key":"S0950268814001812_ref9","unstructured":"European Committee on Antimicrobial Susceptibility Testing (EUCAST). (http:\/\/www.eucast.or)."}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268814001812","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,22]],"date-time":"2020-08-22T11:40:08Z","timestamp":1598096408000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268814001812\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,18]]},"references-count":41,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["S0950268814001812"],"URL":"https:\/\/doi.org\/10.1017\/s0950268814001812","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,18]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2014\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}