{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T23:00:41Z","timestamp":1783983641451,"version":"3.55.0"},"reference-count":25,"publisher":"Cambridge University Press (CUP)","issue":"13","license":[{"start":{"date-parts":[[2015,1,22]],"date-time":"2015-01-22T00:00:00Z","timestamp":1421884800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The aim of this study was to evaluate the quality of life in patients with vascular chronic Q fever at time of diagnosis and during follow-up. Based upon the SF-36 questionnaire, the mean physical and mental health of each patient were assessed at 3-month intervals for up to 18 months. A total of 26 patients were included in the study. At time of diagnosis, the mean physical health and mental health score was 50\u00b76 [95% confidence interval (CI) 46\u00b77\u201354\u00b74] and 44\u00b76 (95% CI 41\u00b76\u201347\u00b75), respectively. During treatment, the mean physical health score declined significantly by 1\u00b77 points each 3 months (<jats:italic>P<\/jats:italic> &lt; 0\u00b7001) to 40\u00b78 (95% CI 34\u00b74\u201345\u00b71). The mean mental health score significantly and steadily increased towards 51\u00b72 (95% CI 46\u00b79\u201354\u00b73) during follow-up (<jats:italic>P<\/jats:italic> = 0\u00b7026). A total of 23% of patients were cured after 18 months of follow-up. In conclusion, quality of life at time of diagnosis for patients with vascular chronic Q fever is lower compared to a similar group of patients, matched for age and gender, with an aortic abdominal aneurysmal disease, and physical health decreases further after starting treatment. Considering the low percentage of cure, the current treatment of vascular chronic Q fever patients may require a separate strategy from that of endocarditis in order to increase survival.<\/jats:p>","DOI":"10.1017\/s0950268814003951","type":"journal-article","created":{"date-parts":[[2015,1,22]],"date-time":"2015-01-22T02:22:07Z","timestamp":1421893327000},"page":"2903-2909","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":4,"title":["Vascular chronic Q fever: quality of life"],"prefix":"10.1017","volume":"143","author":[{"given":"J. C. J. P.","family":"HAGENAARS","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. C.","family":"WEVER","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. O. A.","family":"SHAMELIAN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. S.","family":"VAN PETERSEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"HILBINK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. H. M.","family":"RENDERS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. L.","family":"DE JAGER-LECLERCQ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. L.","family":"MOLL","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O. H. J.","family":"KONING","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,1,22]]},"reference":[{"key":"S0950268814003951_ref21","volume-title":"Applied Longitudinal Data Analysis for Epidemiology. A Practical Guide","author":"Twisk","year":"2003"},{"key":"S0950268814003951_ref11","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.35.3.533"},{"key":"S0950268814003951_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2011.04.013"},{"key":"S0950268814003951_ref24","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/95.8.527"},{"key":"S0950268814003951_ref17","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcq144"},{"key":"S0950268814003951_ref4","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00185-12"},{"key":"S0950268814003951_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(05)70052-9"},{"key":"S0950268814003951_ref16","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-11-112"},{"key":"S0950268814003951_ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2011.12.014"},{"key":"S0950268814003951_ref22","doi-asserted-by":"publisher","DOI":"10.1093\/biomet\/73.1.13"},{"key":"S0950268814003951_ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-007-0357-6"},{"key":"S0950268814003951_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2006.04.016"},{"key":"S0950268814003951_ref18","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1017\/S0950268803008343","article-title":"The effect of C. burnetii infection on the quality of life of patients following an outbreak of Q fever","volume":"130","author":"Hatchette","year":"2003","journal-title":"Epidemiology and Infection"},{"key":"S0950268814003951_ref1","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1128\/CMR.12.4.518","article-title":"Q fever","volume":"12","author":"Maurin","year":"1999","journal-title":"Clinical Microbiology Review"},{"key":"S0950268814003951_ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.08.015"},{"key":"S0950268814003951_ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-012-1749-9"},{"key":"S0950268814003951_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70135-3"},{"key":"S0950268814003951_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2014.03.009"},{"key":"S0950268814003951_ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68266-4"},{"key":"S0950268814003951_ref25","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-12-280"},{"key":"S0950268814003951_ref20","first-page":"264","article-title":"Comparison of methods for the scoring and statistical analysis of SF-36 health profile and summary measures: summary of results from the Medial Outcomes Study","volume":"33","author":"Ware","year":"1995","journal-title":"Medical Care"},{"key":"S0950268814003951_ref12","first-page":"1","article-title":"Diagnosis and Management of Q fever \u2013 United States 2013. Recommendations from CDC and the Q fever Working Group","volume":"62","author":"Anderson","year":"2013","journal-title":"Morbidity and Mortality Weekly Report. Recommendations and Reports"},{"key":"S0950268814003951_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)60733-7"},{"key":"S0950268814003951_ref9","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.2.167"},{"key":"S0950268814003951_ref19","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-11-97"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268814003951","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,20]],"date-time":"2019-04-20T15:09:16Z","timestamp":1555772956000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268814003951\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,22]]},"references-count":25,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["S0950268814003951"],"URL":"https:\/\/doi.org\/10.1017\/s0950268814003951","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,22]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2015\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}