{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T23:00:19Z","timestamp":1783378819715,"version":"3.54.6"},"reference-count":15,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2015,1,23]],"date-time":"2015-01-23T00:00:00Z","timestamp":1421971200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Between 2005 and 2007, <jats:italic>E. coli<\/jats:italic> obtained from clinical diagnostic submissions from cattle, goats, pigs and sheep to government laboratories in England and Wales were tested for sensitivity to 16 antimicrobials. Resistance was most commonly observed against ampicillin, streptomycin, sulphonamides and tetracyclines. Resistance levels varied significantly between species, with isolates from cattle frequently showing the highest levels. Verocytotoxigenic <jats:italic>E. coli<\/jats:italic> (VTEC) expressed less resistance than non-VTEC. Only 19\u00b73% of non-VTEC and 43\u00b75% of VTEC were susceptible to all antimicrobials, while 47\u00b71% and 30\u00b74%, respectively, were resistant to \u2a7e5 antimicrobials. The resistance phenotype SSuT was commonly observed, and isolates resistant to third-generation cephalosporins were also identified. We recommend judicious antimicrobial usage in the livestock industry in order to preserve efficacy.<\/jats:p>","DOI":"10.1017\/s0950268814003963","type":"journal-article","created":{"date-parts":[[2015,1,23]],"date-time":"2015-01-23T07:33:53Z","timestamp":1421998433000},"page":"2653-2659","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":21,"title":["Cross-sectional survey of antibiotic resistance in <i>Escherichia coli<\/i> isolated from diseased farm livestock in England and Wales"],"prefix":"10.1017","volume":"143","author":[{"given":"T. E. A.","family":"CHENEY","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. P.","family":"SMITH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. P.","family":"HUTCHINSON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. A.","family":"BRUNTON","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"PRITCHARD","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. J.","family":"TEALE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2015,1,23]]},"reference":[{"key":"S0950268814003963_ref9","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.8.2166-2169.2000"},{"key":"S0950268814003963_ref1","article-title":"The European Union Summary Report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2011","volume":"11","year":"2013","journal-title":"EFSA Journal"},{"key":"S0950268814003963_ref13","unstructured":"Defra. Zoonoses: Extended-spectrum beta-lactamases (ESBL) in Escherichia coli associated with animals \u2013 Q&A (http:\/\/archive.defra.gov.uk\/foodfarm\/farmanimal\/diseases\/atoz\/zoonoses\/esbl-qa.htm). Accessed 31 October 2012."},{"key":"S0950268814003963_ref10","article-title":"Scientific Opinion on the public health risks of bacterial strains producing extended-spectrum \u00df-lactamases and\/or AmpC \u00df-lactamases in food and food-producing animals","volume":"9","year":"2011","journal-title":"EFSA Journal"},{"key":"S0950268814003963_ref2","doi-asserted-by":"publisher","DOI":"10.1136\/vr.119.17.420"},{"key":"S0950268814003963_ref15","unstructured":"Defra. Strategy for developing and implementing a programme of surveillance for antimicrobial resistance in England and Wales (revised July 2008) (http:\/\/www.vmd.defra.gov.uk\/pdf\/SurveillanceStrategy2008.pdf). Accessed 5 November 2012."},{"key":"S0950268814003963_ref3","volume-title":"Oxford Textbook of Zoonoses","author":"Karmali","year":"2011"},{"key":"S0950268814003963_ref6","doi-asserted-by":"publisher","DOI":"10.1136\/vr.150.19.593"},{"key":"S0950268814003963_ref14","unstructured":"Health Protection Agency. Antimicrobial Resistance and Prescribing in England, Wales and Northern Ireland, 2008. London: Health Protection Agency, 2008."},{"key":"S0950268814003963_ref7","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268807009223"},{"key":"S0950268814003963_ref4","doi-asserted-by":"publisher","DOI":"10.1136\/vr.d915"},{"key":"S0950268814003963_ref11","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.70.2.752-757.2004"},{"key":"S0950268814003963_ref5","unstructured":"Veterinary Medicines Directorate. UK veterinary antibiotic resistance and sales surveillance 2012 (https:\/\/www.vmd.defra.gov.uk\/pdf\/VARSS.pdf). Accessed 23 April 2014."},{"key":"S0950268814003963_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.resmic.2005.03.006"},{"key":"S0950268814003963_ref12","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.04903-0"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268814003963","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,20]],"date-time":"2019-04-20T16:46:41Z","timestamp":1555778801000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268814003963\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,23]]},"references-count":15,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["S0950268814003963"],"URL":"https:\/\/doi.org\/10.1017\/s0950268814003963","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,23]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2015\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}