{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T11:38:47Z","timestamp":1778067527821,"version":"3.51.4"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T00:00:00Z","timestamp":1446768000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Melioidosis is an infectious disease caused by<jats:italic>Burkholderia pseudomallei<\/jats:italic>, a bacterium endemic in Southeast Asia and northern Australia. In New Caledonia, sporadic cases were first described in 2005; since then, more cases have been identified. To improve our understanding of melioidosis epidemiology in New Caledonia, we compared the local cases and<jats:italic>B. pseudomallei<\/jats:italic>isolates with those from endemic areas. Nineteen melioidosis cases have been diagnosed in New Caledonia since 1999, mostly severe and with frequent bacteraemia, leading to three (16%) fatalities. All but one occurred in the North Province. Besides sporadic cases caused by non-clonal strains, we also identified a hotspot of transmission related to a clonal group of<jats:italic>B. pseudomallei<\/jats:italic>that is phylogenetically related to Australian strains.<\/jats:p>","DOI":"10.1017\/s0950268815002770","type":"journal-article","created":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T10:59:19Z","timestamp":1446807559000},"page":"1330-1337","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":6,"title":["Melioidosis in New Caledonia: a dominant strain in a transmission hotspot"],"prefix":"10.1017","volume":"144","author":[{"given":"B.","family":"MELOT","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"COLOT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"LACASSIN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"TARDIEU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"LAPISARDI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"MAYO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. P.","family":"PRICE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. S.","family":"SAROVICH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. J.","family":"CURRIE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0690-9464","authenticated-orcid":false,"given":"C.","family":"GOARANT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2015,11,6]]},"reference":[{"key":"S0950268815002770_ref14","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.5.2068-2079.2003"},{"key":"S0950268815002770_ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S0761-8425(08)71551-1"},{"key":"S0950268815002770_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-706X(99)00064-9"},{"key":"S0950268815002770_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2004.01269.x"},{"key":"S0950268815002770_ref16","doi-asserted-by":"publisher","DOI":"10.3201\/eid1502.081036"},{"key":"S0950268815002770_ref10","first-page":"1","article-title":"Animal health survey in New Caledonia [in French]","volume":"2","author":"Domenech","year":"1984","journal-title":"Revue d'Elevage et de M\u00e9decine V\u00e9t\u00e9rinaire de Nouvelle-Cal\u00e9donie"},{"key":"S0950268815002770_ref13","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.3201\/eid1110.050823","article-title":"Melioidosis in New Caledonia","volume":"11","author":"Le","year":"2005","journal-title":"Emerging Infectious Diseases"},{"key":"S0950268815002770_ref26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2009.02310.x"},{"key":"S0950268815002770_ref3","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.2.383-416.2005"},{"key":"S0950268815002770_ref19","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.12.116"},{"key":"S0950268815002770_ref8","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu764"},{"key":"S0950268815002770_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(08)70003-8"},{"key":"S0950268815002770_ref20","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01036-06"},{"key":"S0950268815002770_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2004.09.008"},{"key":"S0950268815002770_ref22","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1128\/AEM.61.6.2276-2285.1995","article-title":"Nickel-resistant bacteria from anthropogenically nickel-polluted and naturally nickel-percolated ecosystems","volume":"61","author":"Stoppel","year":"1995","journal-title":"Applied and Environmental Microbiology"},{"key":"S0950268815002770_ref2","doi-asserted-by":"publisher","DOI":"10.1086\/318116"},{"key":"S0950268815002770_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(95)90080-2"},{"key":"S0950268815002770_ref25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001991"},{"key":"S0950268815002770_ref24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003586"},{"key":"S0950268815002770_ref23","doi-asserted-by":"crossref","first-page":"4972","DOI":"10.1128\/IAI.65.12.4972-4977.1997","article-title":"Identification and characterization of a two-component regulatory system involved in invasion of eukaryotic cells and heavy-metal resistance in Burkholderia pseudomallei","volume":"65","author":"Jones","year":"1997","journal-title":"Infection and Immunity"},{"key":"S0950268815002770_ref15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0091682"},{"key":"S0950268815002770_ref18","first-page":"543","article-title":"SEAVIEW and PHYLO_WIN: two graphic tools for sequence alignment and molecular phylogeny","volume":"12","author":"Galtier","year":"1996","journal-title":"Computer Applications in the Biosciences"},{"key":"S0950268815002770_ref29","doi-asserted-by":"publisher","DOI":"10.3201\/eid1707.100707"},{"key":"S0950268815002770_ref30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0018343"},{"key":"S0950268815002770_ref28","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1055\/s-0034-1398389","article-title":"Melioidosis: evolving concepts in epidemiology, pathogenesis, and treatment","volume":"36","author":"Currie","year":"2015","journal-title":"Seminars in Respiratory and Critical Care Medicine"},{"key":"S0950268815002770_ref11","unstructured":"Poirier N . Melioidosis: a propos of a clinical case observed in New Caledonia: epidemiology, clinical and therapeutic aspects (MD dissertation) [in French]. Universit\u00e9 de Rennes 1, 2001."},{"key":"S0950268815002770_ref27","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2012.12-0165"},{"key":"S0950268815002770_ref6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1204699"},{"key":"S0950268815002770_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2007.02.024"},{"key":"S0950268815002770_ref17","first-page":"95","article-title":"BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95\/98\/NT","volume":"41","author":"Hall","year":"1999","journal-title":"Nucleic Acids Symposium Series"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268815002770","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T02:11:15Z","timestamp":1599790275000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268815002770\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,6]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["S0950268815002770"],"URL":"https:\/\/doi.org\/10.1017\/s0950268815002770","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,6]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2015\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}