{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:09:17Z","timestamp":1757704157447},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2016,1,8]],"date-time":"2016-01-08T00:00:00Z","timestamp":1452211200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The phylogenetic and epidemiological relationships of 102 <jats:italic>Burkholderia pseudomallei<\/jats:italic> clinical isolates from different geographical and population sources in China were investigated by multilocus sequence typing (MLST). The MLST data were analysed using the e-BURST algorithm, and an unweighted pair-group method with arithmetic mean dendrogram was constructed based on the pair-wise differences in the allelic profiles of the strains. Forty-one sequence types (STs) were identified, of which eight were novel (ST1341, ST1345, ST1346, ST1347, ST1348, ST1349, ST1350, ST1351). No geographical-specific or host population-specific phylogenetic lineages were identified. ST46, ST50, ST55, ST58, ST70 and ST1095 predominated, but ~44% of isolates were assigned to 45 STs illustrating high genetic diversity in the strain collection. Additionally, the phylogenetic relationships of the dominant STs in China showed significant linkeage with <jats:italic>B. pseudomallei<\/jats:italic> isolates from Thailand. Analysis of the <jats:italic>gmhD<\/jats:italic> allele suggests high genetic variation in <jats:italic>B. pseudomallei<\/jats:italic> in China.<\/jats:p>","DOI":"10.1017\/s0950268815003052","type":"journal-article","created":{"date-parts":[[2016,1,8]],"date-time":"2016-01-08T23:18:01Z","timestamp":1452295081000},"page":"1917-1923","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":14,"title":["Multilocus sequence typing of 102 <i>Burkholderia pseudomallei<\/i> strains isolated from 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