{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T13:50:36Z","timestamp":1760709036748},"reference-count":52,"publisher":"Cambridge University Press (CUP)","issue":"13","license":[{"start":{"date-parts":[[2016,3,28]],"date-time":"2016-03-28T00:00:00Z","timestamp":1459123200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Although infection by the pathogenic bacterium <jats:italic>Listeria monocytogenes<\/jats:italic> is relatively rare, consequences can be severe, with a high case-fatality rate in vulnerable populations. A quantitative, probabilistic risk assessment tool was developed to compare estimates of the number of invasive listeriosis cases in vulnerable Canadian subpopulations given consumption of contaminated ready-to-eat delicatessen meats and hot dogs, under various user-defined scenarios. The model incorporates variability and uncertainty through Monte Carlo simulation. Processes considered within the model include cross-contamination, growth, risk factor prevalence, subpopulation susceptibilities, and thermal inactivation. Hypothetical contamination events were simulated. Results demonstrated varying risk depending on the consumer risk factors and implicated product (turkey delicatessen meat without growth inhibitors ranked highest for this scenario). The majority (80%) of listeriosis cases were predicted in at-risk subpopulations comprising only 20% of the total Canadian population, with the greatest number of predicted cases in the subpopulation with dialysis and\/or liver disease. This tool can be used to simulate conditions and outcomes under different scenarios, such as a contamination event and\/or outbreak, to inform public health interventions.<\/jats:p>","DOI":"10.1017\/s0950268816000327","type":"journal-article","created":{"date-parts":[[2016,3,28]],"date-time":"2016-03-28T13:17:30Z","timestamp":1459171050000},"page":"2743-2758","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":11,"title":["Comparing listeriosis risks in at-risk populations using a user-friendly quantitative microbial risk assessment tool and epidemiological data"],"prefix":"10.1017","volume":"144","author":[{"given":"L. E.","family":"FALK","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. A.","family":"FADER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. S.","family":"CUI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. C.","family":"TOTTON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"FAZIL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M.","family":"LAMMERDING","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. A.","family":"SMITH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2016,3,28]]},"reference":[{"key":"S0950268816000327_ref23","unstructured":"Farmland. Hickory smoked hot dogs \u2013 original (http:\/\/www.farmlandfoods.com\/products\/hickory-smoked-hot-dogs-original.html). Accessed 27 September 2015."},{"key":"S0950268816000327_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1605(00)00272-5"},{"key":"S0950268816000327_ref30","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir902"},{"key":"S0950268816000327_ref33","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268805005376"},{"key":"S0950268816000327_ref18","unstructured":"Health Canada. Notice of modification to the list of permitted preservatives to enable the addition of potassium lactate and sodium lactate to standardized meat products and poultry meat products, 2012 (http:\/\/www.hc-sc.gc.ca\/fn-an\/alt_formats\/pdf\/consult\/nom-adm-0001\/document-consultation-eng.pdf). Accessed 27 September 2015."},{"key":"S0950268816000327_ref20","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-67.9.1892"},{"key":"S0950268816000327_ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-4530.2005.033.x"},{"key":"S0950268816000327_ref47","doi-asserted-by":"publisher","DOI":"10.1016\/S0956-7135(96)00035-7"},{"key":"S0950268816000327_ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-003-2225-6"},{"key":"S0950268816000327_ref29","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-60.8.918"},{"key":"S0950268816000327_ref52","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2007.06.005"},{"key":"S0950268816000327_ref5","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268809990914"},{"key":"S0950268816000327_ref3","doi-asserted-by":"publisher","DOI":"10.1086\/376631"},{"key":"S0950268816000327_ref37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2621.2005.tb11451.x"},{"key":"S0950268816000327_ref6","unstructured":"Weatherill D . Report of the independent investigator into the 2008 listeriosis outbreak: Health Canada, 2009 (http:\/\/www.cpha.ca\/uploads\/history\/achievements\/09-lirs-rpt_e.pdf). Accessed 27 September 2015."},{"key":"S0950268816000327_ref1","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2012.1389"},{"key":"S0950268816000327_ref49","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-73.4.612"},{"key":"S0950268816000327_ref38","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-54.4.283"},{"key":"S0950268816000327_ref41","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-14-235"},{"key":"S0950268816000327_ref22","doi-asserted-by":"publisher","DOI":"10.1108\/BFJ-03-2014-0131"},{"key":"S0950268816000327_ref39","doi-asserted-by":"publisher","DOI":"10.1016\/j.meatsci.2012.09.007"},{"key":"S0950268816000327_ref43","unstructured":"World Health Organization. Risk assessment of Listeria monocytogenes in ready-to-eat foods. Technical report, Microbiological Risk Assessment Series, 5th edn: Food & Agriculture Org., 2004."},{"key":"S0950268816000327_ref13","unstructured":"Dewis G . Controlling the temperature in Canadian homes: Statistics Canada, 2008. (Environment accounts and statistics technical paper series; catalogue no. 16\u2013001-M, no. 6.)."},{"key":"S0950268816000327_ref46","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2013.1697"},{"key":"S0950268816000327_ref51","doi-asserted-by":"publisher","DOI":"10.1080\/09540129850124497"},{"key":"S0950268816000327_ref16","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-73.2.312"},{"key":"S0950268816000327_ref36","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-70.11.2620"},{"key":"S0950268816000327_ref28","unstructured":"Statistics Canada. Table 051\u20130001 \u2013 Estimates of population, by age group and sex for July 1, Canada, provinces and territories, annual (persons unless otherwise noted): CANSIM (database). Accessed 27 September 2015."},{"key":"S0950268816000327_ref44","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1992.03480150047035"},{"key":"S0950268816000327_ref8","volume-title":"Compendium of Methods for the Microbiological Examination of Foods","author":"Smith","year":"2013"},{"key":"S0950268816000327_ref12","volume-title":"Risk Analysis: A Quantitative Guide","author":"Vose","year":"2008"},{"key":"S0950268816000327_ref48","unstructured":"Health Canada. Canadian Alcohol and Drug Use Monitoring Survey, 2011 (http:\/\/www.hc-sc.gc.ca\/hc-ps\/drugs-drogues\/stat\/_2011\/summary-sommaire-eng.php). Accessed 27 September 2015."},{"key":"S0950268816000327_ref10","doi-asserted-by":"publisher","DOI":"10.1111\/risa.12235"},{"key":"S0950268816000327_ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2009.06.013"},{"key":"S0950268816000327_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2009.02.007"},{"key":"S0950268816000327_ref19","unstructured":"U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, U.S. Department of Agriculture, Food Safety and Inspection Service, and Centers for Disease Control and Prevention. Quantitative assessment of the relative risk to public health from food-borne Listeria monocytogenes among selected categories of ready-to-eat foods, 2003 (http:\/\/www.fda.gov\/downloads\/Food\/FoodScienceResearch\/UCM197330.pdf) Accessed 27 September 2015."},{"key":"S0950268816000327_ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2013.08.030"},{"key":"S0950268816000327_ref25","doi-asserted-by":"publisher","DOI":"10.1016\/0168-1605(96)00992-0"},{"key":"S0950268816000327_ref35","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X.JFP-11-491"},{"key":"S0950268816000327_ref32","unstructured":"Marsden JL , Salmonella spp. and Listeria monocytogenes risk assessment for production and cooking of blade tenderized beef steaks, 2001 (http:\/\/www.fsis.usda.gov\/OPPDE\/rdad\/FRPubs\/01-013N\/BeefSteaks.pdf). Accessed 27 September 2015."},{"key":"S0950268816000327_ref40","doi-asserted-by":"publisher","DOI":"10.1111\/j.1539-6924.2007.00921.x"},{"key":"S0950268816000327_ref24","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-69.7.1630"},{"key":"S0950268816000327_ref31","unstructured":"Health Canada. 2008 Listeriosis outbreak in Ontario, chronology of events, 2009 (http:\/\/www.health.gov.on.ca\/en\/public\/publications\/disease\/docs\/listeriosis_outbreak_chronology.pdf). Accessed 27 September 2015."},{"key":"S0950268816000327_ref34","unstructured":"Ross T , Listeria monocytogenes in Australian processed meat products: risks and their management: Final report, 2009."},{"key":"S0950268816000327_ref50","unstructured":"Quesenberry H , FSIS comparative risk assessment for Listeria monocytogenes in ready to eat meat and poultry delicatessen meats. Food Safety and Inspection Service, U.S. Department of Agriculture, 2012 (http:\/\/www.fsis.usda.gov\/shared\/PDF\/Comparative_RA_Lm_Report_May2010.pdf). Accessed 27 September 2015."},{"key":"S0950268816000327_ref4","first-page":"6","article-title":"Foodborne illness acquired in the United States \u2013 major pathogens","volume":"17","author":"Scallan","year":"2011","journal-title":"Emerging Infectious Disease"},{"key":"S0950268816000327_ref17","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-72.5.978"},{"key":"S0950268816000327_ref42","doi-asserted-by":"publisher","DOI":"10.1111\/j.1539-6924.2006.00717.x"},{"key":"S0950268816000327_ref7","unstructured":"Health Canada. Policy on Listeria monocytogenes in ready-to-eat foods. Bureau of Microbial Hazards, Food Directorate, Health Products and Food Branch, 2011 (http:\/\/www.hc-sc.gc.ca\/fn-an\/alt_formats\/pdf\/legislation\/pol\/policy_listeria_monocytogenes_2011-eng.pdf). Accessed 27 September 2015."},{"key":"S0950268816000327_ref15","unstructured":"EcoSure. 2007 United States cold temperature evaluation design and summary pages, 2008. (http:\/\/foodrisk.org\/exclusives\/EcoSure\/). Accessed 27 September 2015."},{"key":"S0950268816000327_ref45","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2005.01171.x"},{"key":"S0950268816000327_ref27","doi-asserted-by":"publisher","DOI":"10.12927\/hcq.2008.19859"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268816000327","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,18]],"date-time":"2019-04-18T22:37:05Z","timestamp":1555627025000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268816000327\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,28]]},"references-count":52,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["S0950268816000327"],"URL":"https:\/\/doi.org\/10.1017\/s0950268816000327","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,28]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2016\u00a0This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}