{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T23:08:54Z","timestamp":1788476934454,"version":"build-2803163510"},"reference-count":32,"publisher":"Cambridge University Press (CUP)","issue":"11","license":[{"start":{"date-parts":[[2016,3,28]],"date-time":"2016-03-28T00:00:00Z","timestamp":1459123200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Dengue has become a global problem in past few decades, with half of the world's population at risk of infection. For some countries of Asia and Latin America, severe dengue is a major cause of serious illness and even death in children. Pakistan has been reported as a hyperendemic area for dengue infection. Our study aimed to find seroprevalence of past dengue infection in asymptomatic children of Lahore with no previous history of dengue infection. A total of 400 samples were collected from children aged 1\u201312 years in Lahore using random sampling. The inclusion criteria were children aged 1\u201312 years, who had no previous symptoms of dengue fever during their lives. Children with known immunodeficiency status or fever at the time of recruitment were excluded from the study. Commercially available ELISA kits were used to determine the IgG status in sera of children. The data obtained was entered and analysed using SPSS v. 20.0. The overall prevalence of asymptomatic dengue infection was found to be 25%. There was no statistically significant difference between prevalence of infection in male and female children. There was, however, a strong relationship between increasing age of the child and number of cases with infection, with low incidence in children aged \u2a7d5 years.<\/jats:p>","DOI":"10.1017\/s0950268816000522","type":"journal-article","created":{"date-parts":[[2016,3,28]],"date-time":"2016-03-28T13:17:00Z","timestamp":1459171020000},"page":"2276-2282","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":12,"title":["Seroprevalence of asymptomatic dengue infection in children in Lahore"],"prefix":"10.1017","volume":"144","author":[{"given":"S. N.","family":"MOHSIN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"GHAFOOR","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"SALEEM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"GHOUS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"AASIM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2016,3,28]]},"reference":[{"key":"S0950268816000522_ref27","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1128\/JCM.30.3.545-551.1992","article-title":"Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction","volume":"30","author":"Lanciotti","year":"1992","journal-title":"Journal of Clinical Microbiology"},{"key":"S0950268816000522_ref14","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1968.17.590"},{"key":"S0950268816000522_ref17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012505"},{"key":"S0950268816000522_ref9","unstructured":"Tropical Medical Bureau (http:\/\/www.tmb.ie\/exodus\/news.asp?title=289Dengue-cases-in-Pakistan-show-encouraging-declineandid=184659). Accessed 13 December 2011."},{"key":"S0950268816000522_ref7","unstructured":"WHO. Fact sheet No. 117 (http:\/\/www.who.int\/mediacentre\/factsheets\/fs117\/en\/). Accessed 14 December 2011."},{"key":"S0950268816000522_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)12483-7"},{"key":"S0950268816000522_ref30","first-page":"13","article-title":"Seroprevalence of dengue viral infection in healthy population residing in rural areas of district Rawalpindi","volume":"8","author":"Zafar","year":"2010","journal-title":"International Journal of Pathology"},{"key":"S0950268816000522_ref29","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1128\/CMR.11.3.480","article-title":"Dengue and dengue hemorrhagic fever","volume":"11","author":"Gubler","year":"1998","journal-title":"Clinical Microbiology Reviews"},{"key":"S0950268816000522_ref22","first-page":"107","article-title":"Dengue and dengue hemorrhagic fever in the Americas","volume":"6","author":"Gubler","year":"1987","journal-title":"Puerto Rico Health Sciences Journal"},{"key":"S0950268816000522_ref18","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(95)90412-3"},{"key":"S0950268816000522_ref20","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1992.46.649"},{"key":"S0950268816000522_ref6","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-11-200"},{"key":"S0950268816000522_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/0166-0934(87)90097-8"},{"key":"S0950268816000522_ref11","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1988.38.172"},{"key":"S0950268816000522_ref31","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(96)90286-2"},{"key":"S0950268816000522_ref2","unstructured":"Science Mag (www.sciencemag.org\/news\/2013\/10\/first-new-dengue-virus-50-years). Accessed 25 January 2016."},{"key":"S0950268816000522_ref15","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1999.9656"},{"key":"S0950268816000522_ref23","unstructured":"New US. Army mosquito control technology licensed for deployment against dengue (http:\/\/www.medicalnewstoday.com\/articles\/13006\/php). Accessed 13 November 2011."},{"key":"S0950268816000522_ref10","first-page":"333","article-title":"Clinical factors associated with mortality in dengue infection at a tertiary care center","volume":"41","author":"Almas","year":"2010","journal-title":"Southeast Asian Journal of Tropical Medicine and Public Health"},{"key":"S0950268816000522_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)76460-6"},{"key":"S0950268816000522_ref25","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199204000-00010"},{"key":"S0950268816000522_ref8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0050068"},{"key":"S0950268816000522_ref28","unstructured":"Medscape Clinical Reference (http:\/\/emedicine.medscape.com\/article\/215840-overview). Accessed 15 May 2009."},{"key":"S0950268816000522_ref32","unstructured":"Dengue virus net.com (http:\/\/www.denguevirusnet.com\/aedes-aegypti.html). Accessed 23 January 2016."},{"key":"S0950268816000522_ref1","unstructured":"WHO Media Centre (http:\/\/www.who.int\/mediacentre\/factsheets\/fs117\/en\/). Accessed 15 February 2015."},{"key":"S0950268816000522_ref26","first-page":"129","article-title":"Diagnosing Dengue Fever","volume":"14","author":"Ahmed","year":"2005","journal-title":"Infectious Diseases Journal Pakistan"},{"key":"S0950268816000522_ref5","doi-asserted-by":"crossref","first-page":"239","DOI":"10.3855\/jidc.1017","article-title":"Dengue fever in the Indian subcontinent: an overview","volume":"5","author":"Raheel","year":"2011","journal-title":"Journal of Infection in Developing Countries"},{"key":"S0950268816000522_ref19","doi-asserted-by":"publisher","DOI":"10.1097\/00001432-200210000-00003"},{"key":"S0950268816000522_ref13","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113932"},{"key":"S0950268816000522_ref21","doi-asserted-by":"publisher","DOI":"10.1590\/S1020-49892006000700005"},{"key":"S0950268816000522_ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2008.00678.x"},{"key":"S0950268816000522_ref12","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268898001058"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268816000522","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T21:27:11Z","timestamp":1600378031000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268816000522\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,28]]},"references-count":32,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["S0950268816000522"],"URL":"https:\/\/doi.org\/10.1017\/s0950268816000522","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,28]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2016\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}