{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T11:33:20Z","timestamp":1793705600819,"version":"4.5.1"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","issue":"12","license":[{"start":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T00:00:00Z","timestamp":1464652800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>To evaluate measles incidence and its relevant changes over a 14-year period (2000\u20132014), we analysed data from the regional hospital discharge database on children and adults hospitalized in Tuscany, Italy. A total of 181 paediatric and 413 adult cases were identified. Despite all the efforts towards regional measles elimination, we observed that the overall measles hospitalization rates for children and adults living in Tuscany globally increased from 0\u00b745 to 0\u00b785\/100 000 during the study period (<jats:italic>P<\/jats:italic> = 0\u00b7001) showing fluctuations due to periodic measles outbreaks. Data stratified by age group showed that the hospitalization rate significantly increased in young adults over the study period, confirming an increase in susceptibility to measles in this subpopulation. Conversely, no statistically significant difference was observed in the hospitalization rate in the other age groups. However, children aged &lt;1 year still exhibit the highest hospitalization rate. Pneumonia represented the most common complication in both the adult and children subsets. No death was reported. Measles still represents a public health problem, and national strategies should be implemented, focusing on emergent susceptible subsets, such as infants and young adults.<\/jats:p>","DOI":"10.1017\/s0950268816001023","type":"journal-article","created":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T08:57:08Z","timestamp":1464685028000},"page":"2605-2612","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":10,"title":["Analysis of measles-related hospitalizations in Tuscany from 2000 to 2014"],"prefix":"10.1017","volume":"144","author":[{"given":"E.","family":"BERTI","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"SOLLAI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"ORLANDINI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"GALLI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"DE MARTINO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"CHIAPPINI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2016,5,31]]},"reference":[{"key":"S0950268816001023_ref9","doi-asserted-by":"crossref","first-page":"140","DOI":"10.4161\/hv.34416","article-title":"Factors associated with poor adherence to MMR vaccination in parents who follow vaccination schedule","volume":"11","author":"Restivo","year":"2015","journal-title":"Human Vaccines and Immunotherapeutics"},{"key":"S0950268816001023_ref15","first-page":"16","article-title":"Measles outbreak in adults in Italy","volume":"19","author":"Bassetti","year":"2011","journal-title":"Infezioni in Medicina"},{"key":"S0950268816001023_ref20","first-page":"298","article-title":"Exanthemic diseases (measles, chickenpox, rubella and parotitis). Focus on screening and health surveillance of health workers: results and perspectives of a multicenter working group","volume":"32","author":"Campagna","year":"2010","journal-title":"Giornale Italiano di Medicina del Lavoro ed Ergonomia"},{"key":"S0950268816001023_ref12","doi-asserted-by":"crossref","DOI":"10.2807\/ese.18.20.20480-en","article-title":"Analysis of national measles surveillance data in Italy from October 2010 to December 2011 and priorities for reaching the 2015 measles elimination goal","volume":"18","author":"Filia","year":"2013","journal-title":"Eurosurveillance"},{"key":"S0950268816001023_ref23","unstructured":"American Academy of Pediatrics Committee on Infectious Diseases. Measles. Red Book\u00ae: 2015 Report of the Committee on Infectious Diseases, 30th edn (http:\/\/sitemaster.solutions.aap.org\/DocumentLibrary\/2015RedBookMeasles.pdf)."},{"key":"S0950268816001023_ref10","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/1403494815610182","article-title":"Measles among migrants in the European Union and the European Economic Area","volume":"44","author":"Williams","year":"2016","journal-title":"Scandinavian Journal of Public Health"},{"key":"S0950268816001023_ref18","doi-asserted-by":"crossref","first-page":"832","DOI":"10.15585\/mmwr.mm6430a5","article-title":"Lack of measles transmission to susceptible contacts from a health care worker with probable secondary vaccine failure \u2013 Maricopa County, Arizona, 2015","volume":"64","author":"Jones","year":"2015","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"S0950268816001023_ref13","unstructured":"Italian Health Ministry. 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Accessed 20 August 2015."},{"key":"S0950268816001023_ref25","volume-title":"Epidemiology and prevention of vaccine-preventable diseases","author":"Hamborsky","year":"2015"},{"key":"S0950268816001023_ref4","first-page":"E1","article-title":"Australian vaccine preventable disease epidemiological review series: measles 2000\u20132011","volume":"39","author":"Chiew","year":"2015","journal-title":"Communicable Diseases Intelligence Quarterly Report"},{"key":"S0950268816001023_ref16","first-page":"222","article-title":"A measles outbreak in Catania, Sicily: the importance of high vaccination coverage and early notification of cases for health and economic reasons","volume":"22","author":"Celesia","year":"2014","journal-title":"Infezioni in Medicina"},{"key":"S0950268816001023_ref6","unstructured":"Italian Health Ministry. Ministerial Act, 28 December 1991. Hospital discharge form creation. Gazzetta Ufficiale 17 January 1992, number 13."},{"key":"S0950268816001023_ref1","unstructured":"European Centre for Disease Prevention and Control. Measles surveillance data (http:\/\/ecdc.europa.eu\/en\/healthtopics\/measles\/epidemiological_data\/pages\/annual_epidemiological_reports.aspx). 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Progress toward regional measles elimination \u2013 worldwide, 2000\u20132013","volume":"63","author":"Perry","year":"2014","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"S0950268816001023_ref8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/MOP.0000000000000307","article-title":"Just when you think you know someone: the evolving epidemiologies of measles and pertussis","volume":"28","author":"Zahn","year":"2016","journal-title":"Current Opinion in Pediatrics"},{"key":"S0950268816001023_ref27","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1097\/01.mlr.0000132391.59713.0d","article-title":"Validity of procedure codes in international classification of disease revision, clinical modification administrative data","volume":"42","author":"Quan","year":"2004","journal-title":"Medical Care"},{"key":"S0950268816001023_ref2","unstructured":"Centers for Diseases Control and Prevention. 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