{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T07:08:14Z","timestamp":1761808094557,"version":"3.37.3"},"reference-count":37,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[2016,10,20]],"date-time":"2016-10-20T00:00:00Z","timestamp":1476921600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Suriname is ranked as high-risk country for cervical cancer, but recent national data of HPV prevalence and distribution in cervical cancer is scarce. In a retrospective cross-sectional study, cervical cancer incidence, HPV prevalence and HPV-type-specific distribution were investigated in all cervical cancer cases (<jats:italic>n<\/jats:italic> = 111), diagnosed in two consecutive years. HPV presence and type-specific prevalence were determined in paraffin-embedded biopsies utilizing master-nested multiplex PCR assays, targeting 14 HPV types. The age-standardized incidence rate of cervical cancer was 22\u00b74\/100 000 women, justifying revision of the current international ranking of Suriname. Eleven HPV types were detected, with the most common types in descending order of frequency: 16, 18, 45, 66, 58\/52\/35. HPV16 was predominant, although with markedly low presence (25%). HPV16 or 18 infections were detected in 43% of the cases, while 28% were untyped, implicating a divergent HPV-type distribution in Suriname with significant variation in the prevalence of less common high-risk virus types and\/or presence of HPV16 variants. HPV-type distribution differed between ethnic groups. A vaccination efficacy of just 28\u201330% was anticipated, next to an uneven vaccination impact in different ethnic groups, cautioning Suriname and other multi-ethnic countries to tailor the information presented to different ethnic communities.<\/jats:p>","DOI":"10.1017\/s0950268816002132","type":"journal-article","created":{"date-parts":[[2016,10,20]],"date-time":"2016-10-20T08:57:53Z","timestamp":1476953873000},"page":"245-253","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":12,"title":["Distinctive distribution of HPV genotypes in cervical cancers in multi-ethnic Suriname: implications for prevention and vaccination"],"prefix":"10.1017","volume":"145","author":[{"given":"M. G.","family":"GRUNBERG","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"CHAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2001-9994","authenticated-orcid":false,"given":"M. R.","family":"ADHIN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2016,10,20]]},"reference":[{"key":"S0950268816002132_ref5","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis627"},{"key":"S0950268816002132_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(09)70096-8"},{"key":"S0950268816002132_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/S1286-4579(00)00276-8"},{"key":"S0950268816002132_ref35","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.20727"},{"key":"S0950268816002132_ref14","unstructured":"World Cancer Research Fund International. Cervical cancer statistics (http:\/\/www.wcrf.org\/int\/cancer-facts-figures\/data-specific-cancers\/cervical-cancer-statistics). Accessed 16 June 2015."},{"key":"S0950268816002132_ref21","first-page":"37","article-title":"Microsatellite instability and human papilloma virus genotypes in preneoplastic and neoplastic uterine cervix lesions","volume":"135","author":"Roa","year":"2007","journal-title":"Revista M\u00e9dica de Chile"},{"key":"S0950268816002132_ref19","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.12004"},{"key":"S0950268816002132_ref31","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a112499"},{"key":"S0950268816002132_ref15","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/87.11.796"},{"key":"S0950268816002132_ref11","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19960401)77:7<1329::AID-CNCR16>3.0.CO;2-3"},{"key":"S0950268816002132_ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.05.063"},{"key":"S0950268816002132_ref13","unstructured":"GLOBOCAN 2012. International Agency for Research on Cancer (http:\/\/globocan.iarc.fr\/). 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UNGASS reports \u2013 Global AIDS response progress report Suriname 2010 (http:\/\/www.pancap.org\/en\/component\/jdownloads\/viewdownload\/50-ungass-reports-global-aids-response-progress-report\/115-suriname-2010-country-progress-report-en.html?Itemid=398). Accessed 17 June 2015."},{"key":"S0950268816002132_ref23","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-200104000-00013"},{"key":"S0950268816002132_ref3","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25396"},{"key":"S0950268816002132_ref7","unstructured":"General Bureau of Statistics. The Eighth Population and Housing Census in Suriname (volume I): Demographic and Social Characteristics and Migration. 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