{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T08:27:55Z","timestamp":1771662475579,"version":"3.50.1"},"reference-count":35,"publisher":"Cambridge University Press (CUP)","issue":"9","license":[{"start":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T00:00:00Z","timestamp":1488412800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Diagnosis of latent tuberculosis infection (LTBI) is a concern in haemodialysis (HD) patients. Many studies have compared QuantiFERON-TB Gold In-Tube (QFT-GIT) and tuberculin skin test (TST) for detecting LTBI and reported the<jats:italic>\u03ba<\/jats:italic>statistic of agreement between QFT-GIT and TST in HD patients. The present study aimed to systematically review this literature and conduct meta-analysis of individual studies that estimated the<jats:italic>\u03ba<\/jats:italic>between QFT-GIT with TST among HD patients. All relevant published studies that were available as full-text were obtained by searching Medline (1950), Web of Sciences (1945), Scopus (1973) through May 2016. The<jats:italic>\u03ba<\/jats:italic>was re-estimated from the individual studies and pooled using random effect meta-analysis. Subgroup analysis and meta-regression were applied to evaluate the effect of Bacillus Calmette\u2013Gu\u00e9rin (BCG) vaccination, TST cut-off points, quality of studies, sample size and age on variation of<jats:italic>\u03ba<\/jats:italic>estimate. Eight studies involving 901 HD patients were included in meta-analysis. The pooled<jats:italic>\u03ba<\/jats:italic>estimate was 0\u00b728 (<jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>= 18\u00b74%,<jats:italic>P<\/jats:italic>= 0\u00b7239, 95% confidence intervals 0\u00b722\u20130\u00b734). The discordance of TST\u2212\/QFT-GIT+ was more than TST+\/QFT-GIT\u2212. History of BCG vaccination, TST cut-off points and age are related to variation of<jats:italic>\u03ba<\/jats:italic>estimates. TST and QFT-GIT are not comparable in detecting LTBI in HD patients. The higher TST\u2212\/QFT-GIT+ ratio compared with TST+\/QFT-GIT\u2212 ratio, may indicate the superiority of QFT-GIT over TST for detection LTBI in HD patients.<\/jats:p>","DOI":"10.1017\/s0950268817000334","type":"journal-article","created":{"date-parts":[[2017,3,2]],"date-time":"2017-03-02T06:59:23Z","timestamp":1488437963000},"page":"1824-1833","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":9,"title":["Comparison of QuantiFERON-TB Gold In-Tube (QFT-GIT) and tuberculin skin test (TST) for diagnosis of latent tuberculosis in haemodialysis (HD) patients: a meta-analysis of<i>\u03ba<\/i>estimates"],"prefix":"10.1017","volume":"145","author":[{"given":"E.","family":"AYUBI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"DOOSTI-IRANI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"SANJARI MOGHADDAM","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"KHAZAEI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"MANSORI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"SAFIRI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"SANI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"MOSTAFAVI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2017,3,2]]},"reference":[{"key":"S0950268817000334_ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.02949.x"},{"key":"S0950268817000334_ref32","doi-asserted-by":"publisher","DOI":"10.1159\/000045581"},{"key":"S0950268817000334_ref33","first-page":"989","article-title":"Risk of tuberculosis in dialysis patients: a population-based study","volume":"2","author":"Chia","year":"1998","journal-title":"International Journal of Tuberculosis and Lung Disease"},{"key":"S0950268817000334_ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-012-0291-0"},{"key":"S0950268817000334_ref31","doi-asserted-by":"publisher","DOI":"10.1378\/chest.113.1.25"},{"key":"S0950268817000334_ref25","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqw035"},{"key":"S0950268817000334_ref14","doi-asserted-by":"publisher","DOI":"10.4103\/0971-5916.159297"},{"key":"S0950268817000334_ref21","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000000451"},{"key":"S0950268817000334_ref28","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1797.2011.01559.x"},{"key":"S0950268817000334_ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2009.00469.x"},{"key":"S0950268817000334_ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000045974"},{"key":"S0950268817000334_ref17","first-page":"286","article-title":"Assessment of an Interferon-gamma release assay for the diagnosis of latent tuberculosis infection in haemodialysis patient","volume":"140","author":"Hoffmann","year":"2010","journal-title":"Swiss Medical Weekly"},{"key":"S0950268817000334_ref16","doi-asserted-by":"publisher","DOI":"10.1080\/13102818.2009.10817646"},{"key":"S0950268817000334_ref23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0161983"},{"key":"S0950268817000334_ref29","doi-asserted-by":"publisher","DOI":"10.1007\/s002230010095"},{"key":"S0950268817000334_ref4","first-page":"1192","article-title":"False-positive tuberculin skin tests: what is the absolute effect of BCG and non-tuberculous mycobacteria?","volume":"10","author":"Farhat","year":"2006","journal-title":"International Journal of Tuberculosis and Lung Disease: the Official Journal of the International Union Against Tuberculosis and Lung Disease"},{"key":"S0950268817000334_ref27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02834.x"},{"key":"S0950268817000334_ref6","unstructured":"World Health Organization. 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