{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:29:52Z","timestamp":1793194192837,"version":"4.5.0"},"reference-count":27,"publisher":"Cambridge University Press (CUP)","issue":"10","license":[{"start":{"date-parts":[[2017,5,18]],"date-time":"2017-05-18T00:00:00Z","timestamp":1495065600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>The overall incidence of spinal tuberculosis (TB) appears to be stable or declining in most European countries, but with an increasing proportion of cases in the foreign-born populations. We performed a retrospective observational study (1993\u20132014), including all cases of spinal TB diagnosed at a Barcelona hospital to assess the epidemiological changes. Fifty-four episodes (48\u00b71% males, median age 52 years) of spinal TB were diagnosed. The percentage of foreign-born residents with spinal TB increased from 14% to 45\u00b72% in the last 10 years (<jats:italic>P<\/jats:italic> = 0\u00b7017). Positive <jats:italic>Mycobacterium tuberculosis<\/jats:italic> testing in vertebral specimens was 88\u00b72% (15\/17) for GeneXpert MTB\/RIF. Compared with natives, foreign-born patients were younger (<jats:italic>P &lt;<\/jats:italic> 0\u00b701) and required surgery more often (<jats:italic>P<\/jats:italic> = 0\u00b7003) because of higher percentages of paravertebral abscess (<jats:italic>P<\/jats:italic> = 0\u00b7038), cord compression (<jats:italic>P<\/jats:italic> = 0\u00b705), and persistent neurological sequelae (<jats:italic>P<\/jats:italic> = 0\u00b705). In our setting, one-third of spinal TB cases occurred in non-native residents. Compared with natives, foreign-born patients were younger and had greater severity of the disease. The GeneXpert MTB\/RIF test may be of value for diagnosing spinal TB.<\/jats:p>","DOI":"10.1017\/s0950268817000863","type":"journal-article","created":{"date-parts":[[2017,5,18]],"date-time":"2017-05-18T10:03:27Z","timestamp":1495101807000},"page":"2152-2160","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":17,"title":["The changing epidemiology of spinal tuberculosis: the influence of international immigration in Catalonia, 1993\u20132014"],"prefix":"10.1017","volume":"145","author":[{"given":"M.","family":"PEGHIN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"RODRIGUEZ-PARDO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"SANCHEZ-MONTALVA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"PELLIS\u00c9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"RIVAS","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"TORTOLA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"AGUILAR","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"ALMIRANTE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"PIGRAU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2017,5,18]]},"reference":[{"key":"S0950268817000863_ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2011.01.017"},{"key":"S0950268817000863_ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-012-2337-5"},{"key":"S0950268817000863_ref23","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.92B7.24668"},{"key":"S0950268817000863_ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-004-1148-y"},{"key":"S0950268817000863_ref20","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw778"},{"key":"S0950268817000863_ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-012-2331-y"},{"key":"S0950268817000863_ref18","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199909000-00003"},{"key":"S0950268817000863_ref17","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000509"},{"key":"S0950268817000863_ref14","doi-asserted-by":"publisher","DOI":"10.1086\/322670"},{"key":"S0950268817000863_ref21","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.22.2776"},{"key":"S0950268817000863_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2009.09.011"},{"key":"S0950268817000863_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.eimc.2016.06.002"},{"key":"S0950268817000863_ref12","doi-asserted-by":"publisher","DOI":"10.1179\/1973947815Y.0000000043"},{"key":"S0950268817000863_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tube.2016.07.019"},{"key":"S0950268817000863_ref16","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01459-06"},{"key":"S0950268817000863_ref4","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200209000-00003"},{"key":"S0950268817000863_ref15","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200607-970OC"},{"key":"S0950268817000863_ref26","doi-asserted-by":"publisher","DOI":"10.1007\/PL00011973"},{"key":"S0950268817000863_ref24","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199608150-00014"},{"key":"S0950268817000863_ref13","doi-asserted-by":"publisher","DOI":"10.3201\/eid1209.050553"},{"key":"S0950268817000863_ref2","doi-asserted-by":"publisher","DOI":"10.1086\/605559"},{"key":"S0950268817000863_ref5","volume-title":"Epidemiology and Trends in TBC in Catalonia","year":"2013"},{"key":"S0950268817000863_ref6","unstructured":"Population Register of Catalonia; (www.idescat.cat)."},{"key":"S0950268817000863_ref7","unstructured":"Department of Health. Epidemiology and Trends in TBC in Catalonia. Annual report 2004. 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