{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:41:19Z","timestamp":1760132479989,"version":"3.37.3"},"reference-count":33,"publisher":"Cambridge University Press (CUP)","issue":"15","license":[{"start":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T00:00:00Z","timestamp":1508112000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>Prior studies suggest that the influenza vaccine is protective against some outcomes in hospitalized patients infected with influenza despite vaccination. We utilized surveillance data from Columbus, Ohio to investigate this association over multiple influenza seasons and age groups. Data on laboratory-confirmed influenza-associated hospitalizations were collected as a part of the Influenza Hospitalization Surveillance Project for the 2012\u20132013, 2013\u20132014, and 2014\u20132015 influenza seasons. The association between influenza vaccination status was examined in relation to the outcomes of severe influenza and diagnosis of pneumonia among patients receiving antiviral treatment. Data were analyzed using multivariable logistic regression. We observed no overall association between influenza vaccination status and severe influenza among hospitalized patients. During the 2013\u20132014 season, those who were vaccinated were 41% less likely to be diagnosed with pneumonia compared with those who were unvaccinated (OR = 0\u00b759 95% CI 0\u00b741\u20130\u00b786). The influenza vaccine may provide a secondary preventive function against pneumonia among influenza cases requiring hospitalization. However, a protective effect was only observed in 2013\u20132014, an influenza H1N1 dominant year. Differences in circulating influenza virus strains and vaccine matching to the circulating strains during influenza seasons may impact this association.<\/jats:p>","DOI":"10.1017\/s0950268817002163","type":"journal-article","created":{"date-parts":[[2017,10,15]],"date-time":"2017-10-15T22:31:39Z","timestamp":1508106699000},"page":"3284-3293","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":6,"title":["Influenza vaccination status and outcomes among influenza-associated hospitalizations in Columbus, Ohio (2012\u20132015)"],"prefix":"10.1017","volume":"145","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9932-1095","authenticated-orcid":false,"given":"P. 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K.","family":"BOWER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2017,10,16]]},"reference":[{"key":"S0950268817002163_ref18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0050074"},{"key":"S0950268817002163_ref17","unstructured":"U.S. Census Bureau, Population Division. Annual estimates of the resident population: April 1, 2010 to July 1, 2014. In: Division P , ed. US Census Bureau, 2015."},{"key":"S0950268817002163_ref2","first-page":"1057","article-title":"Estimates of deaths associated with seasonal influenza \u2013 United States, 1976\u20132007","volume":"59","author":"Thompson","year":"2010","journal-title":"MMWR Morbidity and Mortality Weekly Report"},{"key":"S0950268817002163_ref1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis211"},{"key":"#cr-split#-S0950268817002163_ref32.1","unstructured":"2. Flannery B, Chung J . 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