{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T05:33:05Z","timestamp":1769751185518,"version":"3.49.0"},"reference-count":21,"publisher":"Cambridge University Press (CUP)","issue":"6","license":[{"start":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T00:00:00Z","timestamp":1520985600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Measles is an important childhood infection targeted to be eliminated by the World Health Organization (WHO). Virus circulation has not been interrupted in the European Region because high vaccination rates could not be achieved among some countries of the WHO European Region including Turkey. The purpose of this study was to evaluate the laboratory findings of measles cases confirmed in the last nine years, to assess the epidemiological data of the cases, to determine the molecular genotyping studies and to emphasise the importance of laboratory-based surveillance in measles. From 2007 to 2010, only 18 imported cases were detected in Turkey. However, this number increased with a local outbreak of 111 cases in 2011, followed by another outbreak in 2012 in Istanbul that spread countrywide in the following two years; a total of 8661 laboratory-confirmed measles cases were reported from 2012 to 2015. After ELISA detection of a measles IgM-positive result in serum samples of potential measles cases, RT\u2013PCR was performed with urine or nasopharyngeal swab samples of patients, and amplicons were subjected to sequencing. In the samples of 2010 and 2011, D4 and D9 genotypes were mainly detected; as of 2012, the D8 genotype has gained importance. Although D8 was also identified in 2014, in the same year genotype H1 viruses were detected in Turkey for the first time. Therefore, it is important to perform a genotypic analysis of the virus causing the outbreak, analyse epidemiological connections of the contact, determine the source of the outbreak and plan measures based on this information.<\/jats:p>","DOI":"10.1017\/s0950268818000432","type":"journal-article","created":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T04:09:41Z","timestamp":1521000581000},"page":"735-740","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":12,"title":["The importance of serological and molecular analyses for the diagnosis of measles cases and for meeting elimination targets in Turkey from 2007 to 2015"],"prefix":"10.1017","volume":"146","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3815-8036","authenticated-orcid":false,"given":"Yasemin","family":"Cosgun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilek","family":"Guldemir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aslihan","family":"Coskun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sultan","family":"Yolbakan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atila Taner","family":"Kalaycioglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gulay","family":"Korukluoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riza","family":"Durmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2018,3,14]]},"reference":[{"key":"S0950268818000432_ref18","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir118"},{"key":"S0950268818000432_ref5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d3724"},{"key":"S0950268818000432_ref13","article-title":"Measles virus genotyping an important tool in measles outbreak investigation in Norway, 2011","volume":"17","author":"Vainio","year":"2012","journal-title":"Euro Surveillance"},{"key":"S0950268818000432_ref4","first-page":"1605","article-title":"Increased transmission and outbreaks of measles-European Region, 2011","volume":"60","year":"2011","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"S0950268818000432_ref16","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.24548"},{"key":"S0950268818000432_ref9","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir117"},{"key":"S0950268818000432_ref1","unstructured":"WHO Library Cataloguing-in-Publication Data, ISBN 978 92 4 150339 6, World Health Organization (2012) Global Measles And Rubella Strateg\u0131c Plan 2012\u20132020."},{"key":"S0950268818000432_ref12","doi-asserted-by":"publisher","DOI":"10.1086\/377103"},{"key":"S0950268818000432_ref6","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir067"},{"key":"S0950268818000432_ref11","first-page":"55","article-title":"The importance of laboratory confirmation in measles surveillance","volume":"1","author":"Kurugol","year":"2007","journal-title":"Journal of Pediatric Infection"},{"key":"S0950268818000432_ref21","doi-asserted-by":"crossref","first-page":"4","DOI":"10.5070\/D33WD095BT","article-title":"Viral exanthems","volume":"9","author":"Scott","year":"2003","journal-title":"Dermatology Online Journal"},{"key":"S0950268818000432_ref3","unstructured":"The Measles & Rubella Initiative 2014 Annual Report."},{"key":"S0950268818000432_ref14","doi-asserted-by":"publisher","DOI":"10.1086\/368040"},{"key":"S0950268818000432_ref2","volume-title":"Manual of Clinical Microbiology","author":"Murray","year":"2007"},{"key":"S0950268818000432_ref8","unstructured":"Measles, Rubella and Congenital Rubella Syndrome Surveillance (CRS) Circular of the Republic of Turkey Ministry of Health General Directorate of Primary Health Care, Circular 2010\/20."},{"key":"S0950268818000432_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.23714"},{"key":"S0950268818000432_ref17","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.066746-0"},{"key":"S0950268818000432_ref19","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.2610"},{"key":"S0950268818000432_ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.pop.2015.08.006"},{"key":"S0950268818000432_ref7","unstructured":"World Health Organization (2007) Manual for the laboratory diagnosis of measles and rubella infection \u2013 Second Edition, August 2007, Department of Vaccines and Biologicals."},{"key":"S0950268818000432_ref10","doi-asserted-by":"publisher","DOI":"10.1128\/9781555816834.ch31"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268818000432","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,15]],"date-time":"2022-08-15T23:57:13Z","timestamp":1660607833000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268818000432\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,14]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["S0950268818000432"],"URL":"https:\/\/doi.org\/10.1017\/s0950268818000432","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,14]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2018\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}