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The objectives of this study were (1) to describe the microbiological profile of shigella strains isolated in western French Guiana, including antimicrobial susceptibility and the distribution of strains in terms of species and serotypes and (2) to estimate the incidence of shigellosis in children under 5 years old. A retrospective observational study was conducted of 213 cases of shigellosis diagnosed in the biology department of the hospital centre for western French Guiana between 2000 and 2012 in children under 5 years old. The serogroups (formerly known as species) that predominates in French Guiana was<jats:italic>Shigella flexneri<\/jats:italic>. No resistance was observed to fluoroquinolones or to third-generation cephalosporins. The average incidence of shigellosis in children under 5 years old in western French Guiana was estimated at 189.6 cases per 100 000 inhabitants per year. Shigellosis is a public health problem in western French Guiana. These infections suggest the difficulties in accessing safe water sources and the lack of public sanitation. A quadrivalent vaccine containing<jats:italic>Shigella sonnei<\/jats:italic>and three serotypes of<jats:italic>S. flexneri<\/jats:italic>(<jats:italic>S. flexneri<\/jats:italic>2a, 3a and 6) could provide broad coverage against shigella infections.<\/jats:p>","DOI":"10.1017\/s0950268818000912","type":"journal-article","created":{"date-parts":[[2018,4,15]],"date-time":"2018-04-15T10:09:38Z","timestamp":1523786978000},"page":"980-984","update-policy":"http:\/\/dx.doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":9,"title":["Shigella infection in children under 5 years old in western French Guiana"],"prefix":"10.1017","volume":"146","author":[{"given":"M.","family":"Parisot","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Parez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Boukhari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Breurec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Jolivet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2018,4,15]]},"reference":[{"key":"S0950268818000912_ref32","first-page":"1","article-title":"Les \u00e9pid\u00e9mies de typho\u00efde en Guyane fran\u00e7aise, 13 ans de veille et de gestion sanitaires","volume":"20","author":"Mansotte","year":"2009","journal-title":"Bull d'Information en Sant\u00e9 Environnementale"},{"key":"S0950268818000912_ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2011.08.008"},{"key":"S0950268818000912_ref30","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-8-130"},{"key":"S0950268818000912_ref29","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-9-204"},{"key":"S0950268818000912_ref28","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762013000100005"},{"key":"S0950268818000912_ref27","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-4-18"},{"key":"S0950268818000912_ref25","unstructured":"Woerther PL (2012) Emergence, circulation et d\u00e9terminants mol\u00e9culaires des souches d'ent\u00e9robact\u00e9ries productrices de \u00df-lactamases \u00e0 spectre \u00e9tendu (BLSE) chez des populations soumises \u00e0 des pressions de s\u00e9lection variables (thesis). 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