{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:57:26Z","timestamp":1747173446685,"version":"3.40.5"},"reference-count":19,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"unspecified","delay-in-days":59,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2019]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The clinical characteristics of male patients with pulmonary <jats:italic>Mycobacterium avium<\/jats:italic> complex disease have not been clearly defined. We aimed to clarify the clinical characteristics of male patients with pulmonary <jats:italic>Mycobacterium avium<\/jats:italic> complex disease compared with female patients.<\/jats:p><jats:p>We retrospectively reviewed the medical records of patients with pulmonary <jats:italic>Mycobacterium avium<\/jats:italic> complex disease who visited the outpatient clinic of the Shinshu University Hospital between 2003 and 2016 and compared the clinical characteristics of male and female patients.<\/jats:p><jats:p>A total of 234 patients with pulmonary <jats:italic>Mycobacterium avium<\/jats:italic> complex disease were identified (68 men and 166 women). Male patients were significantly older than female patients. Blood examination results showed that the lymphocyte count, total protein level and albumin level were significantly lower in men than in women. Chest imaging findings were broadly categorised into the fibrocavitary and nodular bronchiectasis types. There were no significant differences in chest imaging findings and the time from diagnosis to disease exacerbation between men and women.<\/jats:p><jats:p>During the study period, the incidence of the nodular bronchiectasis type of pulmonary <jats:italic>Mycobacterium avium<\/jats:italic> complex disease in male patients increased compared with previous reports. Men had no difference in time to exacerbation compared with women.<\/jats:p>","DOI":"10.1017\/s0950268819000293","type":"journal-article","created":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T04:18:56Z","timestamp":1551413936000},"source":"Crossref","is-referenced-by-count":2,"title":["Comparison of clinical characteristics of patients with <i>Mycobacterium avium<\/i> complex disease by gender"],"prefix":"10.1017","volume":"147","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7622-173X","authenticated-orcid":false,"given":"Y.","family":"Ikuyama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ushiki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Akahane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Kosaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Kitaguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Urushihata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Yasuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hanaoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2019,3,1]]},"reference":[{"key":"S0950268819000293_ref18","unstructured":"The Research Institute of Tuberculosis\/JATA. The Tuberculosis Surveillance Center in Japan. Available at http:\/\/www.jata.or.jp\/rit\/ekigaku\/index.php\/download_file\/-\/view\/4186\/. 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Ministry of Health, Labor and Welfare in Japan 2014. Available at https:\/\/www.e-stat.go.jp\/stat-search\/files?page=1&layout=datalist&toukei=00450171&tstat=000001041744&cycle=7&year=20140&month=0&tclass1=000001083415. (Accessed 28 June 2018) (in Japanese)."},{"key":"S0950268819000293_ref17","first-page":"679","article-title":"Background factors for casual isolation of Mycobacterium intracellulare from sputum of patients with tuberculosis","volume":"108","author":"Tsukamura","year":"1973","journal-title":"The American Review of Respiratory Disease"},{"key":"S0950268819000293_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2015.01.004"},{"key":"S0950268819000293_ref2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2206.151086"},{"key":"S0950268819000293_ref16","unstructured":"Ministry of Health, Labor and Welfare in Japan (2014) Available at https:\/\/www.mhlw.go.jp\/toukei\/saikin\/hw\/kanja\/14\/dl\/02.pdf. Accessed (2 November 2018) (in Japanese)."}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268819000293","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T17:50:41Z","timestamp":1559929841000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268819000293\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":19,"alternative-id":["S0950268819000293"],"URL":"https:\/\/doi.org\/10.1017\/s0950268819000293","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"type":"print","value":"0950-2688"},{"type":"electronic","value":"1469-4409"}],"subject":[],"published":{"date-parts":[[2019]]},"article-number":"e108"}}