{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:57:52Z","timestamp":1747173472813,"version":"3.40.5"},"reference-count":28,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T00:00:00Z","timestamp":1576022400000},"content-version":"unspecified","delay-in-days":344,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2019]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A large-scale measles outbreak (11 495 reported cases, 60% aged \u226515 years) occurred in Georgia during 2013\u20132015. A nationwide, multistage, stratified cluster serosurvey for hepatitis B and C among persons aged \u226518 years conducted in Georgia in late 2015 provided an opportunity to assess measles and rubella (MR) susceptibility after the outbreak. Residual specimens from 3125 participants aged 18\u201350 years were tested for Immunoglobulin G antibodies against MR using ELISA. Nationwide, 6.3% (95% CI 4.9%\u20137.6%) of the surveyed population were seronegative for measles and 8.6% (95% CI 7.1%\u201310.1%) were seronegative for rubella. Measles susceptibility was highest among 18\u201324 year-olds (10.1%) and declined with age to 1.2% among 45\u201350 year-olds (<jats:italic>P<\/jats:italic>&lt; 0.01). Susceptibility to rubella was highest among 25\u201329 year-olds (15.3%), followed by 18\u201324 year-olds (11.6%) and 30\u201334 year-olds (10.2%), and declined to &lt;5% among persons aged \u226535 years (<jats:italic>P<\/jats:italic>&lt; 0.001). The susceptibility profiles in the present serosurvey were consistent with the epidemiology of recent MR cases and the history of the immunization programme. Measles susceptibility levels &gt;10% among 18\u201324 year-olds in Georgia revealed continued risk for outbreaks among young adults. High susceptibility to rubella among 18\u201334 year-olds indicates a continuing risk for congenital rubella cases.<\/jats:p>","DOI":"10.1017\/s0950268819002048","type":"journal-article","created":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T06:58:44Z","timestamp":1576047524000},"source":"Crossref","is-referenced-by-count":3,"title":["Measles and rubella seroprevalence among adults in Georgia in 2015: helping guide the elimination efforts"],"prefix":"10.1017","volume":"147","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7771-6520","authenticated-orcid":false,"given":"N.","family":"Khetsuriani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Chitadze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Russell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ben Mamou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2019,12,11]]},"reference":[{"key":"S0950268819002048_ref28","first-page":"301","article-title":"Rubella vaccines: WHO position paper","volume":"86","year":"2011","journal-title":"Weekly Epidemiological Record"},{"key":"S0950268819002048_ref26","unstructured":"World Health Organization (2012) Global measles and rubella strategic plan. 2012\u20132020. 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