{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T11:14:11Z","timestamp":1781522051511,"version":"3.54.1"},"reference-count":35,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2020,6,22]],"date-time":"2020-06-22T00:00:00Z","timestamp":1592784000000},"content-version":"unspecified","delay-in-days":173,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2020]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>Spontaneous abortion is considered a public health problem having several causes, including infections. Among the infectious agents, bacteria of the vaginal microbiota and <jats:italic>Ureaplasma parvum<\/jats:italic> have been associated with abortion, but their participation needs to be further elucidated. This study aims to evaluate the influence of <jats:italic>Mollicutes<\/jats:italic> on the development of spontaneous abortion. Women who underwent spontaneous abortion and those with normal birth (control) were studied. Samples of cervical mucus (CM) and placental tissue were collected to identify <jats:italic>Mollicutes<\/jats:italic> using the quantitative polymerase chain reaction methodology. Eighty-nine women who had a miscarriage and 20 women with normal pregnancies were studied. The presence of <jats:italic>Mollicutes<\/jats:italic> in placental tissue increased the chance of developing miscarriage sevenfold. The prevalence of <jats:italic>U. parvum<\/jats:italic> in women who experienced spontaneous abortion was 66.3% in placental tissue. A positive association was observed between the detection of <jats:italic>U. parvum<\/jats:italic> in samples of placental tissue and abortion. There was a significant increase in microbial load in placental tissue for <jats:italic>M. hominis, U. urealyticum<\/jats:italic> and <jats:italic>U. parvum<\/jats:italic> compared to the control group. Detection of <jats:italic>U. parvum<\/jats:italic> in CM in pregnant women can ascend to the region of the placental tissue and trigger a spontaneous abortion.<\/jats:p>","DOI":"10.1017\/s0950268820001302","type":"journal-article","created":{"date-parts":[[2020,6,22]],"date-time":"2020-06-22T04:28:50Z","timestamp":1592800130000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":22,"title":["Association of spontaneous abortion and <i>Ureaplasma parvum<\/i> detected in placental tissue"],"prefix":"10.1017","volume":"148","author":[{"given":"C. N. T.","family":"Oliveira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. T. S.","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. B. M.","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. S. C.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. S.","family":"Freire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. N.","family":"Santos J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}],"article-number":"e126"}}