{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T10:08:24Z","timestamp":1760609304360,"version":"3.40.5"},"reference-count":13,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T00:00:00Z","timestamp":1598400000000},"content-version":"unspecified","delay-in-days":238,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2020]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Despite SARS-CoV-19 infection has a stereotypical clinical picture, isolated cases with unusual manifestations have been reported, some of them being well-known to be triggered by viral infections. However, the real frequency in COVID-19 is unknown. Analysing data of 63 822 COVID patients attending 50 Spanish emergency department (ED) during the COVID outbreak, before hospitalisation, we report frequencies of (myo)pericarditis (0.71\u2030), meningoencephalitis (0.25\u2030), Guillain\u2013Barr\u00e9 syndrome (0.13\u2030), acute pancreatitis (0.71\u2030) and spontaneous pneumothorax (0.57\u2030). Compared with general ED population, COVID patients developed more frequently Guillain\u2013Barr\u00e9 syndrome (odds ratio (OR) 4.55, 95% confidence interval (CI) 2.09\u20139.90), spontaneous pneumothorax (OR 1.98, 95% CI 1.40\u20132.79) and (myo)pericarditis (OR 1.45, 95% CI 1.07\u20131.97), but less frequently pancreatitis (OR 0.44, 95% CI 0.33\u20130.60).<\/jats:p>","DOI":"10.1017\/s0950268820001910","type":"journal-article","created":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T07:17:58Z","timestamp":1598426278000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":39,"title":["Frequency of five unusual presentations in patients with COVID-19: results of the UMC-19-S<sub>1<\/sub>"],"prefix":"10.1017","volume":"148","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7924-9751","authenticated-orcid":false,"given":"\u00d2scar","family":"Mir\u00f3","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pere","family":"Llorens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f2nia","family":"Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascual","family":"Pi\u00f1era","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Burillo-Putze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfonso","family":"Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco Javier","family":"Mart\u00edn-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Gonz\u00e1lez del Castillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2020,8,26]]},"reference":[{"key":"S0950268820001910_ref13","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2017.13.3.227"},{"key":"S0950268820001910_ref12","first-page":"233","article-title":"Analysis of clinical characteristics and outcomes in patients with COVID-19 based on a series of 1000 patients treated in Spanish emergency departments","volume":"32","author":"Gil-Rodrigo","year":"2020","journal-title":"Emergencias"},{"key":"S0950268820001910_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2020.05.022"},{"key":"S0950268820001910_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00339-1"},{"key":"S0950268820001910_ref2","first-page":"221","article-title":"Acute pericarditis secondary to COVID-19","volume":"32","author":"Marschall","year":"2020","journal-title":"Emergencias"},{"key":"S0950268820001910_ref9","doi-asserted-by":"publisher","DOI":"10.1053\/crad.2001.0889"},{"key":"S0950268820001910_ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"},{"key":"S0950268820001910_ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30076-X"},{"key":"S0950268820001910_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12382"},{"key":"S0950268820001910_ref3","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2020.1096"},{"key":"S0950268820001910_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2020.04.021"},{"key":"S0950268820001910_ref11","first-page":"269","article-title":"Collaboration among Spanish emergency departments to promote research: on the creation of the SIESTA (Spanish Investigators in Emergency Situations TeAm) network and the coordination of the UMC-19 (Unusual Manifestations of COVID-19) macroproject","volume":"32","author":"Mir\u00f3","year":"2020","journal-title":"Emergencias"},{"key":"S0950268820001910_ref7","doi-asserted-by":"crossref","DOI":"10.1093\/jtm\/taaa062","article-title":"COVID-19 with spontaneous pneumothorax,pneumomediastinum and subcutaneous emphysema","author":"Wang","year":"2020","journal-title":"Journal of Travel Medicine"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268820001910","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T15:01:34Z","timestamp":1723474894000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268820001910\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":13,"alternative-id":["S0950268820001910"],"URL":"https:\/\/doi.org\/10.1017\/s0950268820001910","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"type":"print","value":"0950-2688"},{"type":"electronic","value":"1469-4409"}],"subject":[],"published":{"date-parts":[[2020]]},"assertion":[{"value":"Copyright \u00a9 The Author(s), 2020. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e189"}}