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Age-standardised seroprevalences were determined in sera from 1009 women of childbearing age residing in Mexico, Brazil, Germany, Poland, Turkey or China using a multiparametric immunoblot containing antigen substrates for antibodies against<jats:italic>Toxoplasma gondii<\/jats:italic>, rubella virus, cytomegalovirus (CMV), herpes simplex viruses (HSV-1, HSV-2),<jats:italic>Bordetella pertussis<\/jats:italic>,<jats:italic>Chlamydia trachomatis<\/jats:italic>, parvovirus B19,<jats:italic>Treponema pallidum<\/jats:italic>and varicella zoster virus (VZV). Seroprevalences for antibodies against HSV-1 were &gt;90% in samples from Brazil and Turkey, whereas the other four countries showed lower mean age-adjusted seroprevalences (range: 62.5\u201387.9%). Samples from Brazilian women showed elevated seroprevalences of antibodies against HSV-2 (40.1%),<jats:italic>C. trachomatis<\/jats:italic>(46.8%) and<jats:italic>B. pertussis<\/jats:italic>(56.6%) compared to the other five countries. Seroprevalences of anti-<jats:italic>T. gondii<\/jats:italic>antibodies (0.5%) and anti-parvovirus B19 antibodies (7.5%) were low in samples from Chinese women, compared to the other five countries. Samples from German women revealed a low age-standardised seroprevalence of anti-CMV antibodies (28.8%) compared to the other five countries. These global differences in immune status of women in childbearing age advocate country-specific prophylaxis strategies to avoid infection with ToRCH pathogens.<\/jats:p>","DOI":"10.1017\/s0950268820002629","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T09:11:10Z","timestamp":1604049070000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":25,"title":["Seroprevalences of antibodies against ToRCH infectious pathogens in women of childbearing age residing in Brazil, Mexico, Germany, Poland, Turkey and China"],"prefix":"10.1017","volume":"148","author":[{"given":"J. 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