{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T02:24:11Z","timestamp":1771986251437,"version":"3.50.1"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T00:00:00Z","timestamp":1606262400000},"content-version":"unspecified","delay-in-days":329,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2020]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>This study aimed at estimating the transmissibility of hepatitis C. The data for hepatitis C cases were collected in six districts in Xiamen City, China from 2004 to 2018. A population-mixed susceptible-infectious-chronic-recovered (SICR) model was used to fit the data and the parameters of the model were calculated. The basic reproduction number (<jats:italic>R<\/jats:italic><jats:sub>0<\/jats:sub>) and the number of newly transmitted cases by a primary case per month (<jats:italic>MNI<\/jats:italic>) were adopted to quantitatively assess the transmissibility of hepatitis C virus (HCV). Eleven curve estimation models were employed to predict the trends of <jats:italic>R<\/jats:italic><jats:sub>0<\/jats:sub> and <jats:italic>MNI<\/jats:italic> in the city. The SICR model fits the reported HCV data well (<jats:italic>P<\/jats:italic> &lt; 0.01). The median <jats:italic>R<\/jats:italic><jats:sub>0<\/jats:sub> of each district in Xiamen is 0.4059. <jats:italic>R<\/jats:italic><jats:sub>0<\/jats:sub> follows the cubic model curve, the compound curve and the power function curve. The median <jats:italic>MNI<\/jats:italic> of each district in Xiamen is 0.0020. <jats:italic>MNI<\/jats:italic> follows the cubic model curve, the compound curve and the power function curve. The transmissibility of HCV follows a decreasing trend, which reveals that under the current policy for prevention and control, there would be a high feasibility to eliminate the transmission of HCV in the city.<\/jats:p>","DOI":"10.1017\/s0950268820002885","type":"journal-article","created":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T06:54:50Z","timestamp":1606287290000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":12,"title":["The transmissibility of hepatitis C virus: a modelling study in Xiamen City, China"],"prefix":"10.1017","volume":"148","author":[{"given":"Yao","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeyu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingzhai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1494-7700","authenticated-orcid":false,"given":"Mikah 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Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e291"}}