{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T21:56:29Z","timestamp":1747173389509,"version":"3.40.5"},"reference-count":10,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T00:00:00Z","timestamp":1613606400000},"content-version":"unspecified","delay-in-days":48,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>We report the development of a regression model to predict the prevalence of severe acute respiratory syndrome coronavirus (SARS-CoV-2) antibodies on a population level based on self-reported symptoms. We assessed participant-reported symptoms in the past 12 weeks, as well as the presence of SARS-CoV-2 antibodies during a study conducted in April 2020 in Ischgl, Austria. We conducted multivariate binary logistic regression to predict seroprevalence in the sample. Participants (<jats:italic>n<\/jats:italic> = 451) were on average 47.4 years old (<jats:sc>s.d.<\/jats:sc> 16.8) and 52.5% female. SARS-CoV-2 antibodies were found in <jats:italic>n<\/jats:italic> = 197 (43.7%) participants. In the multivariate analysis, three significant predictors were included and the odds ratios (OR) for the most predictive categories were cough (OR 3.34, CI 1.70\u20136.58), gustatory\/olfactory alterations (OR 13.78, CI 5.90\u201332.17) and limb pain (OR 2.55, CI 1.20\u20136.50). The area under the receiver operating characteristic curve was 0.773 (95% CI 0.727\u20130.820). Our regression model may be used to estimate the seroprevalence on a population level and a web application is being developed to facilitate the use of the model.<\/jats:p>","DOI":"10.1017\/s0950268821000418","type":"journal-article","created":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T07:58:28Z","timestamp":1613635108000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Estimating seroprevalence of SARS-CoV-2 antibodies using three self-reported symptoms: development of a prediction model based on data from Ischgl, Austria"],"prefix":"10.1017","volume":"149","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4670-7517","authenticated-orcid":false,"given":"Jens","family":"Lehmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes M.","family":"Giesinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerhard","family":"Rumpold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wegene","family":"Borena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludwig","family":"Knabl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Falkensammer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cornelia","family":"Ower","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalena","family":"Sacher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorothee","family":"von Laer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Sperner-Unterweger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Holzner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2021,2,18]]},"reference":[{"key":"S0950268821000418_ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30185-9"},{"key":"S0950268821000418_ref2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-020-00459-7"},{"key":"S0950268821000418_ref7","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22579"},{"key":"S0950268821000418_ref5","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13091"},{"key":"S0950268821000418_ref10","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6947-12-126"},{"key":"S0950268821000418_ref6","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa799"},{"key":"S0950268821000418_ref8","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0916-2"},{"key":"S0950268821000418_ref3","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0857-9"},{"key":"S0950268821000418_ref9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1328"},{"key":"S0950268821000418_ref4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0234765"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268821000418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T04:12:23Z","timestamp":1614571943000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268821000418\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":10,"alternative-id":["S0950268821000418"],"URL":"https:\/\/doi.org\/10.1017\/s0950268821000418","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"type":"print","value":"0950-2688"},{"type":"electronic","value":"1469-4409"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"Copyright \u00a9 The Author(s), 2021. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e52"}}