{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:46:12Z","timestamp":1786999572976,"version":"build-2736575974"},"reference-count":30,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T00:00:00Z","timestamp":1666742400000},"content-version":"unspecified","delay-in-days":298,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The dissemination of\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    producing extended-spectrum beta-lactamase (ESBL-Ec) is evident in the community. A population-based spatial analysis is necessary to investigate community risk factors for ESBL-Ec occurrence. The study population was defined as individuals with ESBL-Ec isolated in Queensland, Australia, from 2010 to 2019. Choropleth maps, global Moran's index and Getis-Ord Gi* were used to describe ESBL-Ec distribution and identify hot spots. Multivariable Poisson regression models with or without spatially structured random effects were performed. A total of 12 786 individuals with ESBL-Ec isolate were identified. The crude incidence rate increased annually from 9.1 per 100 000 residents in 2010 to 49.8 per 100 000 residents in 2019. The geographical distribution of ESBL-Ec changed from random to clustered after 2014, suggesting presence of community-specific factors that can enhance occurrence. Hot spots were more frequently identified in Outback and Far North Queensland, future public health measures to reduce transmission should prioritise these communities. Communities with higher socioeconomic status (RR = 0.66, 95% CI 0.55\u20130.79, per 100 units increase) and higher proportion of residents employed in the agricultural industry (RR = 0.79, 95% CI 0.67\u20130.95, per 10% increase) had lower ESBL-Ec incidence. Risk factors for occurrence appear differential between remote and city settings and this should be further investigated.\n                  <\/jats:p>","DOI":"10.1017\/s0950268822001637","type":"journal-article","created":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T06:37:29Z","timestamp":1666766249000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":9,"title":["Incidence and predictors of\n                    <i>Escherichia coli<\/i>\n                    producing extended-spectrum beta-lactamase (ESBL-Ec) in Queensland, Australia from 2010 to 2019: a population-based spatial analysis"],"prefix":"10.1017","volume":"150","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5803-3831","authenticated-orcid":false,"given":"Weiping","family":"Ling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Cadavid-Restrepo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Furuya-Kanamori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2895-0345","authenticated-orcid":false,"given":"Patrick N. A.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Paterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2022,10,26]]},"reference":[{"key":"S0950268822001637_ref27","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1111\/j.1469-0691.2009.02877.x","article-title":"Seasonal variation in Escherichia coli bloodstream infection: a population-based study","volume":"15","author":"Al-Hasan","year":"2009","journal-title":"Clinical Microbiology and Infection"},{"key":"S0950268822001637_ref24","doi-asserted-by":"crossref","first-page":"e1004776","DOI":"10.1371\/journal.pgen.1004776","article-title":"Dissemination of cephalosporin resistance genes between Escherichia coli strains from farm animals and humans by specific plasmid lineages","volume":"10","author":"de Been","year":"2014","journal-title":"PLoS Genetics"},{"key":"S0950268822001637_ref30","doi-asserted-by":"crossref","first-page":"100220","DOI":"10.1016\/j.onehlt.2021.100220","article-title":"One health drivers of antibacterial resistance: quantifying the relative impacts of human, animal and environmental use and transmission","volume":"12","author":"Booton","year":"2021","journal-title":"One Healh"},{"key":"S0950268822001637_ref17","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"370","author":"von Elm","year":"2007","journal-title":"The Lancet"},{"key":"S0950268822001637_ref3","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1093\/jac\/dkaa399","article-title":"The global prevalence and trend of human intestinal carriage of ESBL-producing Escherichia coli in the community","volume":"76","author":"Bezabih","year":"2021","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"S0950268822001637_ref2","unstructured":"2. Australia Comission on Safety and Quality in Heath Care (2021) AURA 2021: fourth Australian report on antimicrobial use and resistance in human health. Sydney: ACSQHC."},{"key":"S0950268822001637_ref13","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1093\/jac\/dkw443","article-title":"ESBL\/AmpC-producing Enterobacteriaceae in households with children of preschool age: prevalence, risk factors and co-carriage","volume":"72","author":"van den Bunt","year":"2017","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"S0950268822001637_ref15","doi-asserted-by":"crossref","first-page":"taz083","DOI":"10.1093\/jtm\/taz083","article-title":"Risk factors for acquisition of multidrug-resistant Enterobacterales among international travellers: a synthesis of cumulative evidence","volume":"27","author":"Furuya-Kanamori","year":"2020","journal-title":"Journal of Travel Medicine"},{"key":"S0950268822001637_ref21","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/jac\/dkab345","article-title":"Gastric acid suppression, lifestyle factors and intestinal carriage of ESBL and carbapenemase-producing Enterobacterales: a nationwide population-based study","volume":"77","author":"Willems","year":"2021","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"S0950268822001637_ref16","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/S1473-3099(18)30219-6","article-title":"Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis","volume":"18","author":"Nellums","year":"2018","journal-title":"Lancet Infectious Diseases"},{"key":"S0950268822001637_ref19","unstructured":"19. Queensland Government Statistician's Office. Population estimates: Regions. Available at https:\/\/www.qgso.qld.gov.au\/statistics\/theme\/population\/population-estimates\/regions (Accessed 3 October 2021)."},{"key":"S0950268822001637_ref14","first-page":"62","article-title":"Population-level exposures associated with MRSA and ESBL-E. coli infection across district health boards in Aotearoa New Zealand: an ecological study","volume":"133","author":"Blakiston","year":"2020","journal-title":"New Zealand Medical Journal"},{"key":"S0950268822001637_ref25","doi-asserted-by":"crossref","first-page":"e02693","DOI":"10.1128\/mBio.02693-18","article-title":"One health genomic surveillance of Escherichia coli demonstrates distinct lineages and mobile genetic elements in isolates from humans versus livestock","volume":"10","author":"Ludden","year":"2019","journal-title":"mBio"},{"key":"S0950268822001637_ref22","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/s13756-020-00803-9","article-title":"Hand hygiene improvement or antibiotic restriction to control the household transmission of extended-spectrum \u03b2-lactamase-producing Escherichia coli: a mathematical modelling study","volume":"9","author":"Karda\u015b-S\u0142oma","year":"2020","journal-title":"Antimicrobial Resistance and Infection Control"},{"key":"S0950268822001637_ref12","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.cmi.2019.02.026","article-title":"Individual- and community-level risk factors for ESBL Enterobacteriaceae colonization identified by universal admission screening in London","volume":"25","author":"Otter","year":"2019","journal-title":"Clinical Microbiology and Infection"},{"key":"S0950268822001637_ref4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jac\/dkq415","article-title":"Escherichia coli O25b-ST131: a pandemic, multiresistant, community-associated strain","volume":"66","author":"Rogers","year":"2011","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"S0950268822001637_ref26","unstructured":"26. Australian Bureau of Statistics. 1270.0.55.005 \u2013 Australian Statistical Geography Standard (ASGS): Volume 5 \u2013 Remoteness Structure, July 2016. Available at https:\/\/www.abs.gov.au\/ausstats\/abs@.nsf\/Latestproducts\/1270.0.55.005Main Features15July (Accessed 4 April 2022)."},{"key":"S0950268822001637_ref5","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S1473-3099(16)30319-X","article-title":"Import and spread of extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae by international travellers (COMBAT study): a prospective, multicentre cohort study","volume":"17","author":"Arcilla","year":"2017","journal-title":"Lancet Infectious Diseases"},{"key":"S0950268822001637_ref1","doi-asserted-by":"crossref","first-page":"dlab068","DOI":"10.1093\/jacamr\/dlab068","article-title":"Adverse clinical outcomes associated with infections by Enterobacterales producing ESBL (ESBL-E): a systematic review and meta-analysis","volume":"3","author":"Ling","year":"2021","journal-title":"JAC-antimicrobial Resistance"},{"key":"S0950268822001637_ref18","unstructured":"18. Australian Bureau of Statistics. Find Census data. Available at https:\/\/www.abs.gov.au\/census\/find-census-data (Accessed 27 August 2021)."},{"key":"S0950268822001637_ref11","doi-asserted-by":"crossref","first-page":"e0169589","DOI":"10.1371\/journal.pone.0169589","article-title":"Comparative exposure assessment of ESBL-producing Escherichia coli through meat consumption","volume":"12","author":"Evers","year":"2017","journal-title":"PLoS ONE"},{"key":"S0950268822001637_ref7","doi-asserted-by":"crossref","first-page":"e357","DOI":"10.1016\/S2542-5196(19)30130-5","article-title":"Attributable sources of community-acquired carriage of Escherichia coli containing \u03b2-lactam antibiotic resistance genes: a population-based modelling study","volume":"3","author":"Mughini-Gras","year":"2019","journal-title":"The Lancet Planetary Health"},{"key":"S0950268822001637_ref9","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1089\/fpd.2017.2411","article-title":"Are food animals responsible for transfer of antimicrobial-resistant Escherichia coli or their resistance determinants to human populations? A systematic review","volume":"15","author":"Muloi","year":"2018","journal-title":"Foodborne Pathogens and Disease"},{"key":"S0950268822001637_ref6","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1089\/mdr.2022.0035","article-title":"Carriage duration and household transmission of Enterobacterales producing extended-spectrum beta-lactamase in the community: a systematic review and meta-analysis","volume":"28","author":"Ling","year":"2022","journal-title":"Microbial Drug Resistance"},{"key":"S0950268822001637_ref29","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1086\/656748","article-title":"Seasonal and ascending trends in the incidence of carriage of extended-spectrum \u03b2-lactamase\u2013producing Escherichia coli and Klebsiella species in 2 German hospitals","volume":"31","author":"Dipl-Vw","year":"2010","journal-title":"Infection Control and Hospital Epidemiology"},{"key":"S0950268822001637_ref10","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1093\/jac\/dkaa514","article-title":"Local characteristics associated with higher prevalence of ESBL-producing Escherichia coli in community-acquired urinary tract infections: an observational, cross-sectional study","volume":"76","author":"Larramendy","year":"2017","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"S0950268822001637_ref8","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1093\/cid\/ciw283","article-title":"Fecal colonization with extended-spectrum beta-lactamase\u2013producing Enterobacteriaceae and risk factors among healthy individuals: a systematic review and metaanalysis","volume":"63","author":"Karanika","year":"2016","journal-title":"Clinical Infectious Diseases"},{"key":"S0950268822001637_ref20","unstructured":"20. Australian Bureau of Statistics. Australian Statistical Geography Standard (ASGS). Available at https:\/\/www.abs.gov.au\/websitedbs\/D3310114.nsf\/home\/Australian + Statistical + Geography + Standard + (ASGS) (Accessed 3 October 2021)."},{"key":"S0950268822001637_ref23","unstructured":"23. AMR and animal health in Australia. Available at https:\/\/www.amr.gov.au\/about-amr\/amr-australia\/amr-and-animal-health-australia (Accessed 4 April 2022)."},{"key":"S0950268822001637_ref28","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1111\/j.1469-0691.2009.02866.x","article-title":"Seasonal peaks in Escherichia coli infections: possible explanations and implications","volume":"15","author":"Freeman","year":"2009","journal-title":"Clinical Microbiology and Infection"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268822001637","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T03:32:38Z","timestamp":1668483158000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268822001637\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":30,"alternative-id":["S0950268822001637"],"URL":"https:\/\/doi.org\/10.1017\/s0950268822001637","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]},"assertion":[{"value":"Copyright \u00a9 The Author(s), 2022. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e178"}}