{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:48:07Z","timestamp":1793641687034,"version":"4.5.1"},"reference-count":43,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T00:00:00Z","timestamp":1676246400000},"content-version":"unspecified","delay-in-days":43,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The bacterium\n                    <jats:italic>Neisseria meningitidis<\/jats:italic>\n                    causes life-threatening disease worldwide, typically with a clinical presentation of sepsis or meningitis, but can be carried asymptomatically as part of the normal human oropharyngeal microbiota. The aim of this study was to examine\n                    <jats:italic>N. meningitidis<\/jats:italic>\n                    carriage with regard to prevalence, risk factors for carriage, distribution of meningococcal lineages and persistence of meningococcal carriage. Throat samples and data from a self-reported questionnaire were obtained from 2744 university students (median age: 23 years) at a university in Sweden on four occasions during a 12-month period. Meningococcal isolates were characterised using whole-genome sequencing. The carriage rate among the students was 9.1% (319\/3488; 95% CI 8.2\u201310.1). Factors associated with higher carriage rate were age \u226422 years, previous tonsillectomy, cigarette smoking, drinking alcohol and attending parties, pubs and clubs. Female gender and sharing a household with children aged 0\u20139 years were associated with lower carriage. The most frequent genogroups were capsule null locus (\n                    <jats:italic>cnl<\/jats:italic>\n                    ), group B and group Y and the most commonly identified clonal complexes (cc) were cc198 and cc23. Persistent carriage with the same meningococcal strain for 12 months was observed in two students. Follow-up times exceeding 12 months are recommended for future studies investigating long-term carriage of\n                    <jats:italic>N. meningitidis<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1017\/s0950268823000018","type":"journal-article","created":{"date-parts":[[2023,2,12]],"date-time":"2023-02-12T23:11:40Z","timestamp":1676243500000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":20,"title":["Prevalence and persistence of\n                    <i>Neisseria meningitidis<\/i>\n                    carriage in Swedish university students"],"prefix":"10.1017","volume":"151","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1999-3383","authenticated-orcid":false,"given":"S\u00e4ll","family":"Olof","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eriksson","family":"Lorraine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idosa","family":"Berhane A.","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Persson","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnuson","family":"Anders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thulin Hedberg","family":"Sara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sundqvist","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olc\u00e9n","family":"Per","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fredlund","family":"Hans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stenmark","family":"Bianca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e4rndahl","family":"Eva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f6lling","family":"Paula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacobsson","family":"Susanne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,2,13]]},"reference":[{"key":"S0950268823000018_ref20","doi-asserted-by":"publisher","DOI":"10.3201\/eid1709.101762"},{"key":"S0950268823000018_ref29","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268800049943"},{"key":"S0950268823000018_ref43","doi-asserted-by":"publisher","DOI":"10.1016\/S2589-7500(21)00077-7"},{"key":"S0950268823000018_ref8","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.298.6673.569"},{"key":"S0950268823000018_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70251-6"},{"key":"S0950268823000018_ref31","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-020-05080-w"},{"key":"S0950268823000018_ref34","unstructured":"34. The Public Health Agency of Sweden (2021) Meningokockinfektion \u2013 invasiv. [Internet] 2021 [cited 2022\u201310\u201324]. 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