{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T12:12:32Z","timestamp":1793707952501,"version":"4.6.1"},"reference-count":44,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T00:00:00Z","timestamp":1690502400000},"content-version":"unspecified","delay-in-days":208,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>A third nationally representative serosurvey was performed to study the changes in <jats:italic>Toxoplasma gondii (T. gondii)<\/jats:italic> seroprevalence in the Netherlands over a 20-year time span and to identify and confirm risk factors for acquired toxoplasmosis. This cross-sectional study (conducted in 2016\/2017) was designed similarly to the previous two studies (1995\/1996 and 2006\/2007) and included a questionnaire and serum sampling among Dutch residents. Factors associated with seropositivity for <jats:italic>T. gondii<\/jats:italic> were determined using multivariable analysis of the questionnaire-derived data. The earlier observed decrease in <jats:italic>T. gondii<\/jats:italic> seroprevalence between 1995\/1996 and 2006\/2007 (from 40.5% to 26.0%) did not continue into 2016\/2017 (29.9%). Similarly to the previous studies, the seroprevalence increased with age and varied among regions. In all studies, higher <jats:italic>T. gondii<\/jats:italic> seropositivity was associated with increasing age, lower educational level, not living in the Southeast, and eating raw or semi-cooked pork. The incidence of congenital toxoplasmosis was estimated at 1.3\/1000 (95% CI 0.9\u20131.8) live-born children in 2017. As the seroprevalence of <jats:italic>T. gondii<\/jats:italic> in the Netherlands did not decrease over the last decade, an increase in public health awareness is needed and prevention measures may need to be taken to achieve a further reduction in <jats:italic>T. gondii<\/jats:italic> infections in the Netherlands.<\/jats:p>","DOI":"10.1017\/s095026882300122x","type":"journal-article","created":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T09:15:35Z","timestamp":1690535735000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":24,"title":["Seroprevalence of <i>Toxoplasma gondii<\/i> and associated risk factors for infection in the Netherlands: third cross-sectional national study"],"prefix":"10.1017","volume":"151","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6142-8145","authenticated-orcid":false,"given":"Oda E.","family":"van den Berg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9518-5102","authenticated-orcid":false,"given":"Kamelia R.","family":"Stanoeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rens","family":"Zonneveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Hoek-van Deursen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona R.","family":"van der Klis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"van de Kassteele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eelco","family":"Franz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marieke","family":"Opsteegh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9943-0518","authenticated-orcid":false,"given":"Ingrid H. 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