{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:55:16Z","timestamp":1792511716576,"version":"4.5.0"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T00:00:00Z","timestamp":1693353600000},"content-version":"unspecified","delay-in-days":241,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>This study aimed to summarise the findings of the studies assessing the effectiveness of ultraviolet C (UV-C) room disinfection in reducing the incidence rate of healthcare-associated multi-drug-resistant organism (MDRO) infections. A systematic screening was conducted using PubMed, EMBASE, and Scopus for randomised controlled trials (RCTs), quasi-experimental studies, and before\u2013after studies, which assessed the efficacy of the UV-C disinfectant system in reducing the incidence of MDRO infections. A random-effects model was used for the analysis. Effect sizes were described as incidence rate ratio (IRR) with 95% confidence intervals (CI). Nine studies were included, all of which were conducted in the USA. No statistically significant reduction in <jats:italic>Clostridioides difficile<\/jats:italic> (CD) (IRR: 0.90, 95% CI; 0.62\u20131.32) and vancomycin-resistant enterococcal (VRE) infection rates (IRR 0.72, 95% CI; 0.38\u20131.37) was observed with the use of UV-C, but the risk of Gram-negative rod infection was reduced (IRR 0.82, 95% CI; 0.68\u20130.99).<\/jats:p>","DOI":"10.1017\/s0950268823001371","type":"journal-article","created":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T07:32:23Z","timestamp":1693380743000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":25,"title":["Effectiveness of ultraviolet-C disinfection systems for reduction of multi-drug resistant organism infections in healthcare settings: A systematic review and meta-analysis"],"prefix":"10.1017","volume":"151","author":[{"given":"YanLin","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinzhi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4362-9888","authenticated-orcid":false,"given":"Qian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,8,30]]},"reference":[{"key":"S0950268823001371_r8","doi-asserted-by":"publisher","DOI":"10.1111\/1475-6773.13135"},{"key":"S0950268823001371_r11","doi-asserted-by":"publisher","DOI":"10.1533\/9780857096692.2.413"},{"key":"S0950268823001371_r6","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn104"},{"key":"S0950268823001371_r23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2020.08.030"},{"key":"S0950268823001371_r18","article-title":"The PRISMA 2020 statement: anupdated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ."},{"key":"S0950268823001371_r29","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciac776"},{"key":"S0950268823001371_r33","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2013.08.009"},{"key":"S0950268823001371_r5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0282141"},{"key":"S0950268823001371_r1","doi-asserted-by":"publisher","DOI":"10.5455\/2394-6040.ijcmph20141114"},{"key":"S0950268823001371_r2","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S177247"},{"key":"S0950268823001371_r26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2021.03.009"},{"key":"S0950268823001371_r28","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2016.222"},{"key":"S0950268823001371_r31","doi-asserted-by":"publisher","DOI":"10.1586\/eri.11.166"},{"key":"S0950268823001371_r13","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis839"},{"key":"S0950268823001371_r19","first-page":"l4898","article-title":"Rob 2: A revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"British Medical Journal (Clinical Research Edition)"},{"key":"S0950268823001371_r34","doi-asserted-by":"publisher","DOI":"10.2166\/wst.2003.0193"},{"key":"S0950268823001371_r9","doi-asserted-by":"publisher","DOI":"10.1177\/1757177415570104"},{"key":"S0950268823001371_r25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2021.08.005"},{"key":"S0950268823001371_r14","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e3283630f04"},{"key":"S0950268823001371_r12","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-14-187"},{"key":"S0950268823001371_r16","doi-asserted-by":"publisher","DOI":"10.1017\/S095026882000148X"},{"key":"S0950268823001371_r36","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis335"},{"key":"S0950268823001371_r17","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2017.226"},{"key":"S0950268823001371_r3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0274248"},{"key":"S0950268823001371_r27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2015.07.006"},{"key":"S0950268823001371_r15","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2014.36"},{"key":"S0950268823001371_r37","doi-asserted-by":"publisher","DOI":"10.1086\/499406"},{"key":"S0950268823001371_r30","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2020.05.004"},{"key":"S0950268823001371_r32","doi-asserted-by":"publisher","DOI":"10.1128\/aem.49.6.1361-1365.1985"},{"key":"S0950268823001371_r38","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1216064"},{"key":"S0950268823001371_r22","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciab896"},{"key":"S0950268823001371_r24","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31588-4"},{"key":"S0950268823001371_r20","unstructured":"[20] National Heart Lung and Blood Institute (2014) Study Quality Assessment Tools | NHLBI, NIH. 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