{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:03:06Z","timestamp":1792652586004,"version":"4.5.0"},"reference-count":60,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T00:00:00Z","timestamp":1694044800000},"content-version":"unspecified","delay-in-days":249,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>Rodents and shrews are major reservoirs of various pathogens that are related to zoonotic infectious diseases. The purpose of this study was to investigate co-infections of zoonotic pathogens in rodents and shrews trapped in four provinces of China. We sampled different rodent and shrew communities within and around human settlements in four provinces of China and characterised several important zoonotic viral, bacterial, and parasitic pathogens by PCR methods and phylogenetic analysis. A total of 864 rodents and shrews belonging to 24 and 13 species from <jats:italic>RODENTIA and EULIPOTYPHLA orders<\/jats:italic> were captured, respectively. For viral pathogens, two species of hantavirus (Hantaan orthohantavirus and Caobang orthohantavirus) were identified in 3.47% of rodents and shrews. The overall prevalence of <jats:italic>Bartonella<\/jats:italic> spp., Anaplasmataceae, <jats:italic>Babesia<\/jats:italic> spp., <jats:italic>Leptospira<\/jats:italic> spp., Spotted fever group Rickettsiae, <jats:italic>Borrelia<\/jats:italic> spp., and <jats:italic>Coxiella burnetii<\/jats:italic> were 31.25%, 8.91%, 4.17%, 3.94%, 3.59%, 3.47%, and 0.58%, respectively. Furthermore, the highest co-infection status of three pathogens was observed among <jats:italic>Bartonella<\/jats:italic> spp., <jats:italic>Leptospira<\/jats:italic> spp., and Anaplasmataceae with a co-infection rate of 0.46%. Our results suggested that species distribution and co-infections of zoonotic pathogens were prevalent in rodents and shrews, highlighting the necessity of active surveillance for zoonotic pathogens in wild mammals in wider regions.<\/jats:p>","DOI":"10.1017\/s0950268823001450","type":"journal-article","created":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T09:21:08Z","timestamp":1694078468000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":9,"title":["Zoonotic pathogens identified in rodents and shrews from four provinces, China, 2015\u20132022"],"prefix":"10.1017","volume":"151","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3236-4389","authenticated-orcid":false,"given":"Shen","family":"Tian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao-Gui","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan-Shuang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao-Rong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Hou","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"En-Nian","family":"Pu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Qiong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Jin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4981-1483","authenticated-orcid":false,"given":"Li-Qun","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Lin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Hong","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3887-9079","authenticated-orcid":false,"given":"Yue-Hong","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,9,7]]},"reference":[{"key":"S0950268823001450_r15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0010446"},{"key":"S0950268823001450_r19","doi-asserted-by":"publisher","DOI":"10.1038\/s41426-018-0052-y"},{"key":"S0950268823001450_r52","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2008.02266.x"},{"key":"S0950268823001450_r12","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12717"},{"key":"S0950268823001450_r8","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2022.2065930"},{"key":"S0950268823001450_r9","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-022-03310-8"},{"key":"S0950268823001450_r29","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.895886"},{"key":"S0950268823001450_r16","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-022-02566-2"},{"key":"S0950268823001450_r60","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.15-0517"},{"key":"S0950268823001450_r22","first-page":"716","article-title":"Pathogen investigation of rodents in the western ground crossings of inner Mongolia","volume":"24","author":"Ning","year":"2020","journal-title":"Chinese Journal of Disease Control and Prevention"},{"key":"S0950268823001450_r33","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.584814"},{"key":"S0950268823001450_r34","first-page":"70","article-title":"Epidemiological characteristics of hemorrhagic fever with renal syndrome in China, 2004\u20132021","volume":"38","author":"Deng","year":"2023","journal-title":"Disease Surveillance"},{"key":"S0950268823001450_r42","unstructured":"[42] An, CH , Chen, BB , Lyu, W , Nie, SM , Li, SZ , Fan, SP , Sun, YX , Liu, JR , Li, DM and Xu, JR (2020) Species investigated among rodents from Shaanxi Province of China. 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