{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T03:56:57Z","timestamp":1794023817628,"version":"4.8.0"},"reference-count":38,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["815439"],"award-info":[{"award-number":["815439"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>To inform coverage by potential vaccines, we aimed to systematically review evidence on the prevalence and distribution of non-typhoidal <jats:italic>Salmonella enterica<\/jats:italic> serogroups and serovars. We searched four databases from inception through 4 June 2021. Articles were included that reported at least one non-typhoidal <jats:italic>S. enterica<\/jats:italic> strain by serogroup or serovar isolated from a normally sterile site. Of serogrouped isolates, we pooled the prevalence of serogroup O:4, serogroup O:9, and other serogroups using random-effects meta-analyses. Of serotyped isolates, we pooled the prevalence of <jats:italic>Salmonella<\/jats:italic> Typhimurium (member of serogroup O:4), <jats:italic>Salmonella<\/jats:italic> Enteritidis (member of serogroup O:9), and other serovars. Of 82 studies yielding 24,253 serogrouped isolates, the pooled prevalence (95% CI) was 44.6% (36.2%\u201348.2%) for serogroup O:4, 45.5% (37.0%\u201349.1%) for serogroup O:9, and 9.9% (6.1%\u201313.3%) for other serogroups. Of serotyped isolates, the pooled prevalence (95%CI) was 36.8% (29.9%\u201344.0%) for <jats:italic>Salmonella<\/jats:italic> Typhimurium, 37.8% (33.2%\u201342.4%) for <jats:italic>Salmonella<\/jats:italic> Enteritidis, and 18.4% (11.4%\u201322.9%) for other serovars. Of global serogrouped non-typhoidal <jats:italic>Salmonella<\/jats:italic> isolates from normally sterile sites, serogroup O:4 and O:9 together accounted for 90%, and among serotyped isolates, serovars Typhimurium and Enteritidis together accounted for 75%. Vaccine development strategies covering serogroups O:4 and O:9, or serovars Typhimurium and Enteritidis, have the potential to prevent the majority of non-typhoidal <jats:italic>Salmonella<\/jats:italic> invasive disease.<\/jats:p>","DOI":"10.1017\/s0950268823001693","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T08:31:07Z","timestamp":1697617867000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":33,"title":["Prevalence and distribution of non-typhoidal <i>Salmonella enterica<\/i> serogroups and serovars isolated from normally sterile sites: A global systematic review"],"prefix":"10.1017","volume":"152","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9237-4904","authenticated-orcid":false,"given":"Nienke N.","family":"Hagedoorn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1523-8244","authenticated-orcid":false,"given":"Shruti","family":"Murthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5746-1321","authenticated-orcid":false,"given":"Megan","family":"Birkhold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6952-9840","authenticated-orcid":false,"given":"Christian S.","family":"Marchello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4529-102X","authenticated-orcid":false,"given":"John A.","family":"Crump","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Vacc-iNTS Consortium Collaborators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2023,10,18]]},"reference":[{"key":"S0950268823001693_r1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(19)30418-9"},{"key":"S0950268823001693_r35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0008121"},{"key":"S0950268823001693_r29","unstructured":"[29] PROSPERO Register (2022) Prevalence of serogroup and serovar distribution in invasive non-typhoidal salmonella disease. Available at https:\/\/www.crd.york.ac.uk\/prospero\/display_record.php?RecordID=376658."},{"key":"S0950268823001693_r5","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/169.3.547"},{"key":"S0950268823001693_r24","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23071749"},{"key":"S0950268823001693_r27","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofad041"},{"key":"S0950268823001693_r38","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30458-6"},{"key":"S0950268823001693_r12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2021.06.029"},{"key":"S0950268823001693_r32","doi-asserted-by":"publisher","DOI":"10.1136\/jech-2013-203104"},{"key":"S0950268823001693_r21","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.7.3457-3467.2002"},{"key":"S0950268823001693_r2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61752-2"},{"key":"S0950268823001693_r33","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7414.557"},{"key":"S0950268823001693_r37","doi-asserted-by":"publisher","DOI":"10.1016\/j.cll.2019.05.001"},{"key":"S0950268823001693_r19","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa514"},{"key":"S0950268823001693_r6","doi-asserted-by":"publisher","DOI":"10.1086\/650733"},{"key":"S0950268823001693_r34","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.00374-22"},{"key":"S0950268823001693_r26","unstructured":"[26] World Health Organization (n.d.). Immunization, Vaccines and Biologicals - Nontyphoidal salmonella disease. Available at https:\/\/www.who.int\/teams\/immunization-vaccines-and-biologicals\/diseases\/nontyphoidal-salmonella-disease."},{"key":"S0950268823001693_r8","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46375-0"},{"key":"S0950268823001693_r16","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11844-z"},{"key":"S0950268823001693_r9","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(21)00615-0"},{"key":"S0950268823001693_r4","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.87.4.580"},{"key":"S0950268823001693_r15","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy898"},{"key":"S0950268823001693_r28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000097"},{"key":"S0950268823001693_r31","unstructured":"[31] World Bank Data (2022) The World by Income and Region. Available at https:\/\/unstats.un.org\/unsd\/methodology\/m49\/overview\/."},{"key":"S0950268823001693_r36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1008850"},{"key":"S0950268823001693_r3","first-page":"1","volume-title":"Antigenic Formulae of the Salmonella Serovars","author":"Grimont","year":"2007"},{"key":"S0950268823001693_r10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005118"},{"key":"S0950268823001693_r25","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9020165"},{"key":"S0950268823001693_r14","unstructured":"[14] Centers for Disease Control and Prevention (2018) National enteric disease surveillance: Salmonella annual report, 2016. Available at https:\/\/www.cdc.gov\/nationalsurveillance\/pdfs\/2016-Salmonella-report-508.pdf."},{"key":"S0950268823001693_r20","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.4.2135-2141.2000"},{"key":"S0950268823001693_r30","unstructured":"[30] United Nations (n.d.) Standard country or area codes for statistical use (M49). Available at https:\/\/unstats.un.org\/unsd\/methodology\/m49\/overview\/."},{"key":"S0950268823001693_r13","first-page":"e05500","article-title":"The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2017","volume":"16","year":"2018","journal-title":"EFSA Journal"},{"key":"S0950268823001693_r18","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3644"},{"key":"S0950268823001693_r23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006522"},{"key":"S0950268823001693_r22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005493"},{"key":"S0950268823001693_r7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0007782"},{"key":"S0950268823001693_r11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004857"},{"key":"S0950268823001693_r17","doi-asserted-by":"publisher","DOI":"10.3201\/eid2011.141175"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268823001693","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T07:35:31Z","timestamp":1704353731000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268823001693\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,18]]},"references-count":38,"alternative-id":["S0950268823001693"],"URL":"https:\/\/doi.org\/10.1017\/s0950268823001693","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,18]]},"assertion":[{"value":"\u00a9 The Author(s), 2023. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e4"}}