{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T02:44:08Z","timestamp":1783997048038,"version":"3.55.0"},"reference-count":9,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2024,12,5]],"date-time":"2024-12-05T00:00:00Z","timestamp":1733356800000},"content-version":"unspecified","delay-in-days":339,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>Between February and April 2018, <jats:italic>Salmonella typhimurium<\/jats:italic> within a unique 5-single nucleotide polymorphism (SNP) address was isolated from 28 cases with links to a small rural area of Northeast England, with five cases prospectively identified by whole genome sequencing (WGS). Infections had a severe clinical picture with ten cases hospitalized (36%), two cases with invasive disease, and two deaths reported. Interviews determined that 24 cases (86%) had been exposed to a local independent butcher\u2019s shop (Butcher A).<\/jats:p>\n\t  <jats:p>A case-control study using controls recruited by systematic digit dialling established that cases were 68 times more likely to have consumed cooked meat from Butcher A (Adjusted OR 68.1; 95% CI: 1.9\u20132387.6; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.02). <jats:italic>Salmonella typhimurium<\/jats:italic> genetically highly related to 28 of the outbreak cases was also isolated from a sample of cooked meat on sale in the premises.<\/jats:p>\n\t  <jats:p>Epidemiological and microbiological investigations suggest this outbreak was likely associated with the consumption of ready-to-eat foods supplied by the implicated butcher. A relatively large number of cases were involved despite the rurality of the food business, with cases resident across the Northeast and Yorkshire identified using WGS, demonstrating the benefit of timely sequencing information to community outbreak investigations.<\/jats:p>","DOI":"10.1017\/s0950268824001547","type":"journal-article","created":{"date-parts":[[2024,12,5]],"date-time":"2024-12-05T11:16:12Z","timestamp":1733397372000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":1,"title":["Genetically identified <i>Salmonella typhimurium<\/i> outbreak linked to a rural Butcher\u2019s Shop, February\u2013March 2018, North East England"],"prefix":"10.1017","volume":"152","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3750-7158","authenticated-orcid":false,"given":"Nicola","family":"Love","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana\u00efs","family":"Painset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Aird","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayley","family":"Coleman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirley","family":"Sorrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Stoker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Manley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2024,12,5]]},"reference":[{"key":"S0950268824001547_r2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268807009223"},{"key":"S0950268824001547_r1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2011.238386"},{"key":"S0950268824001547_r3","doi-asserted-by":"publisher","DOI":"10.1016\/j.fm.2008.01.001"},{"key":"S0950268824001547_r4","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.1752"},{"key":"S0950268824001547_r5","doi-asserted-by":"publisher","DOI":"10.1016\/j.fm.2017.02.012"},{"key":"S0950268824001547_r8","first-page":"mgen001059","article-title":"Implementation of routine genomic surveillance provided insights into a locally acquired outbreak caused by a rare clade of Salmonella enterica serovar Enteritidis in Queensland, Australia","volume":"9","author":"Rathnayake","year":"2023","journal-title":"Microbial Genomics"},{"key":"S0950268824001547_r7","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2017.22.49.17-00037"},{"key":"S0950268824001547_r9","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2023.28.27.2300309"},{"key":"S0950268824001547_r6","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268816001941"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268824001547","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,5]],"date-time":"2024-12-05T11:16:14Z","timestamp":1733397374000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268824001547\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":9,"alternative-id":["S0950268824001547"],"URL":"https:\/\/doi.org\/10.1017\/s0950268824001547","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"\u00a9 The Author(s), 2024. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e154"}}