{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:24:25Z","timestamp":1759883065284,"version":"build-2065373602"},"reference-count":29,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"unspecified","delay-in-days":29,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>Cellulitis, a common subcutaneous infection, is influenced by host, pathogen, and environmental factors. Previous studies have shown seasonal patterns in adult cellulitis, suggesting temperature as a risk factor. This study investigated seasonal patterns in paediatric cellulitis in Jerusalem\u2019s semi-arid climate. A single-center retrospective cohort study reviewed medical records of 2,219 hospitalized children under 18 with cellulitis between 1990 and 2020. Demographic, clinical, temperature, and humidity data were collected. Results revealed a significant sinusoidal pattern for limb cellulitis (LC) but for other body sites, with summer peaks and winter nadirs (<jats:italic>P<\/jats:italic> &lt; 0.01). August showed the highest incidence, tripling that of February. Age groups 1-6 and 6-12 demonstrated the largest seasonal differences (<jats:italic>P<\/jats:italic> = 0.004, <jats:italic>P<\/jats:italic> = 0.008). Over three decades, paediatric hospitalized LC cases increased by 71% (<jats:italic>P<\/jats:italic> &lt; 0.001), correlating with rising temperatures. Elevated ambient temperature seven days prior to diagnosis was a risk factor for LC development (OR = 1.02, <jats:italic>P<\/jats:italic> = 0.03). This study highlights the cyclic seasonal pattern of paediatric LC, peaking in summer. The significant increase in cases over time, coupled with rising temperatures, suggests climate change as a contributing factor. These findings could inform public health strategies for cellulitis prevention and management in children.<\/jats:p>","DOI":"10.1017\/s0950268825000032","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T03:37:43Z","timestamp":1738208263000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Global climate change and seasonal variation of cellulitis in hospitalized children: a 30\u00a0year retrospective study"],"prefix":"10.1017","volume":"153","author":[{"given":"Orli","family":"Megged","sequence":"first","affiliation":[{"name":"Hebrew University of Jerusalem"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allon","family":"Raphael","sequence":"additional","affiliation":[{"name":"Shaare Zedek Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amalia","family":"Burstyn","sequence":"additional","affiliation":[{"name":"The Hebrew University of 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