{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:17:24Z","timestamp":1791227844245,"version":"4.1.0"},"reference-count":22,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T00:00:00Z","timestamp":1757289600000},"content-version":"unspecified","delay-in-days":250,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n\t  <jats:p>Toxoplasmosis during pregnancy can cause congenital malformations and fetal death. This study aimed to estimate the <jats:italic>Toxoplasma gondii<\/jats:italic> seroprevalence among pregnant women participating in the 2021 French national perinatal survey and identify associated factors. All women giving birth in France during the study period were invited to participate. Data collected included demographic information, nationality, socio-economic status, education level, and <jats:italic>Toxoplasma gondii<\/jats:italic> serological status. Women were classified as seropositive if IgG antibodies were present or if seroconversion occurred during pregnancy. Univariate and multivariate Poisson regression analyses with robust error variance were used to estimate prevalence ratios and identify factors associated with seropositivity. Among 12,612 women, the overall seroprevalence was 25.9%, and 0.22% seroconverted during pregnancy. Seroprevalence increased by 5% with every 5-year age increment and was significantly higher in the French overseas territories of Mayotte (75.0%), La R\u00e9union (35.8%), and French Guiana (33.3%). Seroprevalence was also higher among women with lower educational levels (47.4% for primary education) and those of Sub-Saharan African nationality (52.0%). Geographic and socio-demographic variations may reflect dietary and environmental diversity. Despite declining seroprevalence in France, continued public health efforts, particularly among high-risk populations, remain critical to minimize the impact of congenital toxoplasmosis.<\/jats:p>","DOI":"10.1017\/s0950268825100502","type":"journal-article","created":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T03:07:18Z","timestamp":1757300838000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":11,"title":["Estimating the national seroprevalence of <i>Toxoplasma gondii<\/i> infection in pregnant women, France 2021"],"prefix":"10.1017","volume":"153","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7989-0661","authenticated-orcid":false,"given":"Sara","family":"Mazzilli","sequence":"first","affiliation":[{"name":"French National Public Health Agency (Sant\u00e9 publique France)"},{"name":"European Centre for Disease Prevention and Control (ECDC)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8368-8485","authenticated-orcid":false,"given":"Mathieu","family":"Tourdjman","sequence":"additional","affiliation":[{"name":"French National Public Health Agency (Sant\u00e9 publique France)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3011-9267","authenticated-orcid":false,"given":"Harold","family":"No\u00ebl","sequence":"additional","affiliation":[{"name":"French National Public Health Agency (Sant\u00e9 publique France)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Maisa","sequence":"additional","affiliation":[{"name":"French National Public Health Agency (Sant\u00e9 publique France)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Villena","sequence":"additional","affiliation":[{"name":"University Reims Champagne-Ardenne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Le-Ray","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Institut Sant\u00e9 des femmes, U1153, INSERM, INRAE"},{"name":"Assistance Publique-H\u00f4pitaux de Paris, H\u00f4pital Cochin, FHU pr\u00e9ma"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"ENP2021 study group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2025,9,8]]},"reference":[{"key":"S0950268825100502_r22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0221709"},{"key":"S0950268825100502_r14","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10050973"},{"key":"S0950268825100502_r3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16412-X"},{"key":"S0950268825100502_r4","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.05013-11"},{"key":"S0950268825100502_r8","first-page":"122","article-title":"La toxoplasmose cong\u00e9nitale : Mise en place d\u2019un dispositif de surveillance en France","volume":"14\u201315","author":"King","year":"2008","journal-title":"Bulletin Epidemiologique Hebdomadaire"},{"key":"S0950268825100502_r7","article-title":"National perinatal survey demonstrates a decreasing seroprevalence of Toxoplasma gondii infection among pregnant women in France, 1995 to 2016: Impact for screening policy","volume":"26","author":"Robinson","year":"2021","journal-title":"Euro Surveillance: bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin"},{"key":"S0950268825100502_r2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2009.04.003"},{"key":"S0950268825100502_r6","first-page":"1183","article-title":"Toxoplasmosis, the mother and the child","volume":"22","author":"Desmonts","year":"1965","journal-title":"Archives Francaises de 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Bmj"},{"key":"S0950268825100502_r12","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-3-21"},{"key":"S0950268825100502_r21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005648"},{"key":"S0950268825100502_r11","unstructured":"[11] Cinelli, H , et al. (2022) Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, sant\u00e9 publique France. Enqu\u00eate Nationale p\u00e9rinatale - Rapport 2021."}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268825100502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T16:17:37Z","timestamp":1759853857000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268825100502\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":22,"alternative-id":["S0950268825100502"],"URL":"https:\/\/doi.org\/10.1017\/s0950268825100502","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"\u00a9 The Author(s), 2025. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e107"}}