{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T12:41:36Z","timestamp":1785415296551,"version":"3.56.0"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"unspecified","delay-in-days":158,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Progress in reducing global malaria incidence has slowed in recent years, demonstrating the need for new vector control tools to complement existing interventions in reaching global malaria control targets. Spatial repellents (SRs) can reduce pathogen transmission by altering the behaviors of Anopheles spp. mosquito vectors. A recent cluster-randomized control trial in western Kenya found that SRs reduced first-time infections by 33.4% in a highly-endemic setting with substantial insecticide resistance and high coverage of insecticide treated nets. We modeled the likely impact of the SR intervention in this setting under different deployment strategies, with the goal of identifying the best overall and per-product strategies. Continuous monthly SR deployment with 100% coverage caused the greatest (45.1%) reduction in infections versus no SR, although some seasonal approaches averted more infections per SR product. Six months of SR use starting in October caused a 36.4% reduction in infections and eight months starting in September reduced infections by 44.7%. This study identified optimum and efficient SR use strategies and highlights the importance of SR protection during periods of low and increasing transmission. When resources are limited, the coverage, deployment strategy, and timing of SR deployment all play a key role in maximizing product impact.<\/jats:p>","DOI":"10.1017\/s095026882610171x","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T08:19:23Z","timestamp":1780906763000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Optimizing the impact of a novel spatial repellent on malaria incidence in Western Kenya"],"prefix":"10.1017","volume":"154","author":[{"given":"Tiffany","family":"Huwe","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00mkhxb43","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Notre Dame"},{"name":"University of Notre Dame"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9354-0414","authenticated-orcid":false,"given":"Cristian","family":"Koepfli","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00mkhxb43","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Notre Dame"},{"name":"University of Notre Dame"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric O.","family":"Ochomo","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04r1cxt79","id-type":"ROR","asserted-by":"publisher"}],"name":"Kenya Medical Research Institute"},{"id":[{"id":"https:\/\/ror.org\/03svjbs84","id-type":"ROR","asserted-by":"publisher"}],"name":"Liverpool School of Tropical Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John E.","family":"Gimnig","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/042twtr12","id-type":"ROR","asserted-by":"publisher"}],"name":"Centers for Disease Control and Prevention"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole L.","family":"Achee","sequence":"additional","affiliation":[{"name":"University of Notre Dame"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Grieco","sequence":"additional","affiliation":[{"name":"University of Notre Dame"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Abong\u2019o","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04r1cxt79","id-type":"ROR","asserted-by":"publisher"}],"name":"Kenya Medical Research Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Moshi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04r1cxt79","id-type":"ROR","asserted-by":"publisher"}],"name":"Kenya Medical Research Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7518-4014","authenticated-orcid":false,"given":"Alex","family":"Perkins","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00mkhxb43","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Notre Dame"},{"name":"University of Notre Dame"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9062-6100","authenticated-orcid":false,"given":"Sean M.","family":"Moore","sequence":"additional","affiliation":[{"name":"University of Notre Dame"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,6,8]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S095026882610171X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T09:10:56Z","timestamp":1782465056000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S095026882610171X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"alternative-id":["S095026882610171X"],"URL":"https:\/\/doi.org\/10.1017\/s095026882610171x","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"\u00a9 The Author(s), 2026. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:\/\/creativecommons.org\/licenses\/by\/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e85"}}