{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T09:03:33Z","timestamp":1785402213805,"version":"3.56.0"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"unspecified","delay-in-days":176,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Maternal syphilis and congenital syphilis (CS) have been increasing globally, but there are limited data from Fiji. We performed secondary analysis of clinical trial data of intrapartum azithromycin given to pregnant women to determine the prevalence of maternal syphilis and estimate the incidence of probable CS. Healthy, pregnant women at a tertiary hospital were routinely tested for syphilis, and their infants, were enrolled between July 2019 and January 2022. World Health Organisation case definitions for maternal and CS were used. Of the 2112 women enrolled, 2073 (98.2%) were tested for syphilis; 82.7% (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a01715) were iTaukei (indigenous Fijians), and the median age was 27\u00a0years (interquartile range [IQR] 23\u201332). The maternal syphilis prevalence was 6.6% (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0137). The majority (85.4%,\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0117) of women with positive serological result received at least one dose of benzathine penicillin 30\u00a0days prior to delivery. There were 139 infants born to mothers with positive serological results. The 2.5-year pooled incidence of probable CS was 212 per 100000 livebirths. Confirmation of CS was not possible as results of polymerase chain reaction test of cerebrospinal fluid were not available. Fiji has a substantial burden of maternal and CS. To eliminate mother-to-child transmission, improvements in testing and follow-up are needed, along with comprehensive data and confirmatory testing to accurately determine disease burden.\n                  <\/jats:p>","DOI":"10.1017\/s0950268826101782","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T03:29:55Z","timestamp":1782444595000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Maternal and congenital syphilis in Fiji 2019\u20132022: a secondary analysis of clinical trial data"],"prefix":"10.1017","volume":"154","author":[{"given":"Stephanie","family":"Clark","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/048fyec77","id-type":"ROR","asserted-by":"publisher"}],"name":"Asia-Pacific Health, Murdoch Children\u2019s Research Institute"},{"name":"Ministry of Health & Medical Services"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8425-6497","authenticated-orcid":false,"given":"Aneley","family":"Getahun Strobel","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/016899r71","id-type":"ROR","asserted-by":"publisher"}],"name":"The Peter Doherty Institute for Infection and Immunity"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maeve","family":"Hume-Nixon","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/048fyec77","id-type":"ROR","asserted-by":"publisher"}],"name":"Asia-Pacific Health, Murdoch Children\u2019s Research Institute"},{"id":[{"id":"https:\/\/ror.org\/01ej9dk98","id-type":"ROR","asserted-by":"publisher"}],"name":"The University of Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tupou","family":"Ratu","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/048fyec77","id-type":"ROR","asserted-by":"publisher"}],"name":"Asia-Pacific Health, Murdoch Children\u2019s Research Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cattram D.","family":"Nguyen","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/048fyec77","id-type":"ROR","asserted-by":"publisher"}],"name":"Asia-Pacific Health, Murdoch Children\u2019s Research Institute"},{"id":[{"id":"https:\/\/ror.org\/01ej9dk98","id-type":"ROR","asserted-by":"publisher"}],"name":"The University of Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7998-0942","authenticated-orcid":false,"given":"Eleanor","family":"Neal","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/048fyec77","id-type":"ROR","asserted-by":"publisher"}],"name":"Asia-Pacific Health, Murdoch Children\u2019s Research Institute"},{"id":[{"id":"https:\/\/ror.org\/01ej9dk98","id-type":"ROR","asserted-by":"publisher"}],"name":"The University of Melbourne"},{"id":[{"id":"https:\/\/ror.org\/048fyec77","id-type":"ROR","asserted-by":"publisher"}],"name":"Murdoch Children\u2019s Research Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atifa","family":"Mohammed","sequence":"additional","affiliation":[{"name":"Ministry of Health & Medical Services"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laila","family":"Sauduadua","sequence":"additional","affiliation":[{"name":"Ministry of Health & Medical Services"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelera","family":"Sakumeni","sequence":"additional","affiliation":[{"name":"Ministry of Health & Medical Services"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilisapeci","family":"Tuibeqa","sequence":"additional","affiliation":[{"name":"Ministry of Health & Medical Services"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona","family":"Russell","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/048fyec77","id-type":"ROR","asserted-by":"publisher"}],"name":"Asia-Pacific Health, Murdoch Children\u2019s Research Institute"},{"id":[{"id":"https:\/\/ror.org\/01ej9dk98","id-type":"ROR","asserted-by":"publisher"}],"name":"The University of Melbourne"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,6,26]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268826101782","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T09:42:49Z","timestamp":1785231769000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268826101782\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"alternative-id":["S0950268826101782"],"URL":"https:\/\/doi.org\/10.1017\/s0950268826101782","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"\u00a9 The Author(s), 2026. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided that no alterations are made and the original article is properly cited. The written permission of Cambridge University Press or the rights holder(s) must be obtained prior to any commercial use and\/or adaptation of the article.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e104"}}