{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T06:47:37Z","timestamp":1792392457609,"version":"4.4.0"},"reference-count":36,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"unspecified","delay-in-days":291,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The\n                    <jats:italic>Histoplasma capsulatum<\/jats:italic>\n                    complex clusters cryptic species with genetic diversities linked to their geographic distribution and virulence. The American continent harbours its highest diversity, making this region the main axis for\n                    <jats:italic>H. capsulatum<\/jats:italic>\n                    spread. Species of this complex cause respiratory-systemic mycosis known as histoplasmosis. Infection occurs through the inhalation of fungal propagules that grow in sites such as caves, mines, and abandoned buildings, where environments rich in organic matter containing micronutrients present in bat and bird guano favour the development of these fungal pathogens. This research was conducted in the state of Nayarit, Mexico, where the combination of environmental factors and the constant occurrence of bats in urban and rural areas contributes to the proliferation of\n                    <jats:italic>H. capsulatum<\/jats:italic>\n                    . The presence of the fungus was detected by nested-PCR using a specific marker (Hcp100) for\n                    <jats:italic>H. capsulatum<\/jats:italic>\n                    , either in guano or in bat organ samples collected in the municipalities of Tepic, Santa Mar\u00eda del Oro (SAMAO), and La Yesca, Nayarit. Out of 27 guano samples analysed by nested-PCR, 21 were positive for\n                    <jats:italic>H. capsulatum<\/jats:italic>\n                    , while of the 12 bats studied, only five revealed infections. The fungus was isolated from a lung sample of a nectarivorous bat (\n                    <jats:italic>Glossophaga mutica<\/jats:italic>\n                    ) by culture. The results suggest a potential risk to exposed populations, including different specialized workers and tourists who explored bat roosts. Avoiding guano accumulation, restricting access to bat roosts, and implementing bat-exclusion strategies in homes are general recommendations to prevent fungal infections.\n                  <\/jats:p>","DOI":"10.1017\/s0950268826102143","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T06:34:16Z","timestamp":1792391656000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["The presence of\n                    <i>Histoplasma capsulatum<\/i>\n                    in environments from the state of Nayarit, Mexico, reveals a potential risk of infection for human populations"],"prefix":"10.1017","volume":"154","author":[{"given":"Gabriela Rosario","family":"Pe\u00f1a-Sandoval","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0576q1t15","id-type":"ROR","asserted-by":"publisher"}],"name":"Universidad Aut\u00f3noma de Nayarit Unidad Acad\u00e9mica de Agricultura"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Rafael","family":"Nolasco-Luna","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0576q1t15","id-type":"ROR","asserted-by":"publisher"}],"name":"Universidad Aut\u00f3noma de Nayarit Unidad Acad\u00e9mica de Agricultura"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn Janeth","family":"Aquino-Navarro","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0576q1t15","id-type":"ROR","asserted-by":"publisher"}],"name":"Universidad Aut\u00f3noma de Nayarit Unidad Acad\u00e9mica de Agricultura"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arlette","family":"Galv\u00e1n-Gonz\u00e1lez","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0576q1t15","id-type":"ROR","asserted-by":"publisher"}],"name":"Universidad Aut\u00f3noma de Nayarit Unidad Acad\u00e9mica de Agricultura"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Rodr\u00edguez-Arellanes","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01tmp8f25","id-type":"ROR","asserted-by":"publisher"}],"name":"Universidad Nacional Autonoma de Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5011-5939","authenticated-orcid":false,"given":"Maria Lucia","family":"Taylor","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01tmp8f25","id-type":"ROR","asserted-by":"publisher"}],"name":"Universidad Nacional Autonoma de Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,10,19]]},"reference":[{"key":"S0950268826102143_r10","doi-asserted-by":"publisher","DOI":"10.1016\/j.cimid.2014.03.002"},{"key":"S0950268826102143_r31","first-page":"46","article-title":"[first isolation of Histoplasma capsulatum from the urban bat Eumops bonariensis]","volume":"37","author":"Canteros","year":"2005","journal-title":"Revista Argentina de Microbiolog\u00eda"},{"key":"S0950268826102143_r34","first-page":"937","article-title":"Molecular detection of Histoplasma capsulatum in insectivorous and frugivorous bats in southeastern Brazil","volume":"56","author":"Santos","year":"2018","journal-title":"Medical Mycology"},{"key":"S0950268826102143_r32","doi-asserted-by":"publisher","DOI":"10.1017\/S095026881000289X"},{"key":"S0950268826102143_r12","first-page":"102","article-title":"Identification of the source of histoplasmosis infection in two captive maras (Dolichotis patagonum) from the same colony by using molecular and immunologic assays","volume":"41","author":"Reyes-Montes","year":"2009","journal-title":"Revista Argentina de Microbiolog\u00eda"},{"key":"S0950268826102143_r11","first-page":"192","article-title":"Natural infection by Histoplasma capsulatum in wild mammals","volume":"11","author":"Vargas-Y\u00e1\u00f1ez","year":"1998","journal-title":"Revista del Instituto Nacional de Enfermedades Respiratorias"},{"key":"S0950268826102143_r24","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.4.1506-1509.2001"},{"key":"S0950268826102143_r15","doi-asserted-by":"publisher","DOI":"10.1126\/science.135.3509.1135.a"},{"key":"S0950268826102143_r18","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a120973"},{"key":"S0950268826102143_r2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30306-7"},{"key":"S0950268826102143_r20","doi-asserted-by":"publisher","DOI":"10.1016\/j.femsim.2005.05.017"},{"key":"S0950268826102143_r6","doi-asserted-by":"publisher","DOI":"10.1016\/j.riam.2012.12.007"},{"key":"S0950268826102143_r23","volume-title":"Identificaci\u00f3n de los murci\u00e9lagos de M\u00e9xico, Clave de Campo","author":"Medell\u00edn","year":"2008"},{"key":"S0950268826102143_r29","first-page":"251","volume-title":"La Biodiversidad en Nayarit. 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