{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:24:21Z","timestamp":1759335861961},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[1997,8,1]],"date-time":"1997-08-01T00:00:00Z","timestamp":870393600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1997,8]]},"abstract":"<jats:p>A total of 368 blood specimens were resampled from a serum \ncollection containing 2914 blood \nsamples which were collected by a random sampling in Taiwan in 1991. The \nplaque reduction \nneutralization test was applied to evaluate the neutralizing ability to \ntwo strains of Japanese \nencephalitis viruses, i.e. Nakayama (the present vaccine strain) and JE5 \n(a Taiwan isolate). The \nresult revealed that antibodies against JE virus were present in each \nstratified age group. \nAntibody positive rates were both highest in the group older than 70 \nyears although the lowest \nrates were located in different groups. In addition, the result showed \nthat the immunogenicity \npotency of the antibody induced by the vaccine strain did not have a \ngood coverage against \nJE5. The rate of neutralizing antibodies above the level of protective \nefficacy of the present \nvaccine was limited as low as 37\u00b793%. Efficacy of the vaccine \nused at present was apparently \nnot efficient. Consideration of a more promising vaccine may be necessary.<\/jats:p>","DOI":"10.1017\/s095026889700753x","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:29:39Z","timestamp":1027762179000},"page":"79-83","source":"Crossref","is-referenced-by-count":18,"title":["Assessment of neutralizing antibodies elicited by a vaccine \n(Nakayama) strain of Japanese encephalitis virus in Taiwan"],"prefix":"10.1017","volume":"119","author":[{"given":"W. R.-H.","family":"SHYU","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.-C.","family":"WANG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"CHIN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.-J.","family":"CHEN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1997,8,1]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S095026889700753X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T12:19:31Z","timestamp":1567426771000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S095026889700753X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,8]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1997,8]]}},"alternative-id":["S095026889700753X"],"URL":"https:\/\/doi.org\/10.1017\/s095026889700753x","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,8]]}}}