{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T20:20:35Z","timestamp":1769372435203,"version":"3.49.0"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[1997,8,1]],"date-time":"1997-08-01T00:00:00Z","timestamp":870393600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1997,8]]},"abstract":"<jats:p><jats:italic>Cryptosporidium parvum<\/jats:italic> infections of domestic animals \ncan have a considerable economic \nimpact and as oocysts are voided in the faeces of infected hosts, \nenvironmental contamination \nwith agricultural waste has also become a matter of concern. Since only \nviable oocysts are \npotentially infectious, the numbers of oocysts excreted during infection \ncan have important \nimplications for both veterinary and public health. During the course of \ninfection in \nexperimentally infected lambs, oocyst viability was assessed by a fluorogenic \nvital dyes assay \nand by a maximized <jats:italic>in vitro<\/jats:italic> excystation assay. The excreted \noocyst populations contained a \nhigher proportion of viable oocysts 5\u201311 days post infection (d.p.i.) \nthan later in the infection. \nOocyst viability declined consistently 11\u201315 d.p.i. and coincided \nwith periods when peaks in \nserum and intestinal anti-<jats:italic>Cryptosporidium<\/jats:italic> antibodies have been \nreported to occur. Infected \nlambs excreted a mean of 4\u00b78 (standard error \n[<jats:sc>S.E.<\/jats:sc>]\u00b10\u00b74)\u00d710<jats:sup>9<\/jats:sup> \noocysts per g of faeces, of which \nhalf were non-viable and therefore of no significance for disease transmission. \nThis study demonstrates that the numbers of viable oocysts excreted by infected \nlambs is smaller than previously suspected.<\/jats:p>","DOI":"10.1017\/s0950268897007590","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:23:42Z","timestamp":1027761822000},"page":"105-108","source":"Crossref","is-referenced-by-count":24,"title":["SHORT PAPER <i>Cryptosporidium parvum<\/i>: oocyst excretion and \nviability patterns in experimentally infected lambs"],"prefix":"10.1017","volume":"119","author":[{"given":"Z.","family":"BUKHARI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. V.","family":"SMITH","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1997,8,1]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268897007590","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T12:19:34Z","timestamp":1567426774000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268897007590\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,8]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1997,8]]}},"alternative-id":["S0950268897007590"],"URL":"https:\/\/doi.org\/10.1017\/s0950268897007590","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,8]]}}}