{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:02:26Z","timestamp":1788566546360,"version":"build-2803163510"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[1997,12,1]],"date-time":"1997-12-01T00:00:00Z","timestamp":880934400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1997,12]]},"abstract":"<jats:p>Enterotoxigenic <jats:italic>Escherichia coli<\/jats:italic> (ETEC) adhere to \n\nthe intestinal mucosa by a number of \n\nfimbrial colonization factors (CFs) that have been claimed to induce only\n \n\ntype-specific \n\nimmunity. However, adult Bangladeshi patients infected with CFA\/I-expressing\n \n\nbacteria, \n\ndeveloped significant plasma IgA antibody responses, as determined by enzyme-linked\n \n\nimmunosorbent assay, not only against the homologous fimbriae \n\nbut also against several \n\nheterologous CFs, i.e. CS1, CS2, CS4 and PCFO166 fimbriae. In contrast,\n \n\nNorth American \n\nvolunteers, who had probably not been infected by ETEC previously, \n\nresponded with serum \n\nIgA against CFA\/I fimbriae but not against any other CFs after \n\nsymptomatic infection with \n\nCFA\/I-expressing ETEC. Thus, infection with CFA\/I-expressing \n\nbacteria may boost immune \n\nresponses against CFs with a related amino acid sequence in \n\npreviously primed subjects.<\/jats:p>","DOI":"10.1017\/s0950268897008200","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T13:23:42Z","timestamp":1027776222000},"page":"391-393","source":"Crossref","is-referenced-by-count":12,"title":["Infection with colonization factor antigen I-expressing \n\nenterotoxigenic <i>Escherichia coli<\/i> boosts antibody responses \n\nagainst heterologous colonization factors in primed subjects"],"prefix":"10.1017","volume":"119","author":[{"given":"A.","family":"RUDIN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"WIKLUND","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"WENNER\u00c5S","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"QADRI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[1997,12,1]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268897008200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,11]],"date-time":"2019-05-11T19:45:43Z","timestamp":1557603943000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268897008200\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,12]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,12]]}},"alternative-id":["S0950268897008200"],"URL":"https:\/\/doi.org\/10.1017\/s0950268897008200","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,12]]}}}