{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T05:28:01Z","timestamp":1789450081641,"version":"build-2803163510"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[1998,8,1]],"date-time":"1998-08-01T00:00:00Z","timestamp":901929600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1998,8]]},"abstract":"<jats:p>Three cohorts of Danish male military recruits (<jats:italic>n<\/jats:italic>=1069)\n \nwere studied for pharyngeal \nmeningococcal carriage during 3 months at different seasons: 39\u201347%\n of entrants were \nmeningococcal carriers and the carriage rate remained constant over time\n and season. \nHowever, individual changes in the carrier state occurred frequently, and\n after 3 months 34% \nhad changed carrier state on one or more occasions. Initially, a loss of\n carriage predominated; \non the other hand almost 20% of non-carriers had acquisition of meningococci\n within the first \nmonth. The serological phenotypes of the 670 carrier strains were compared\n with those of 261 \ninvasive strains recovered concurrently from patients with meningococcal\n disease country-wide. \nBoth carrier strains and invasive strains were phenotypically heterogeneous.\n Almost 60% of \nthe invasive strains belonged to three phenotypes: \nB[ratio   ]15[ratio   ]P1.7, 16, C[ratio   ]2a[ratio   ]P1.2, 5 and C[ratio   ]2b[ratio   ]P1.2,\n 5. \nIn contrast, these phenotypes only amounted to 3\u00b72% of the carrier\n strains, among which no \nphenotype was found with a prevalence above 4\u00b79%. However, 30% of\n the carrier strains had \nserological phenotypes identical to those of 80% of the invasive strains.\n Our results indicated \nthat the transmission rate of potential pathogenic carrier strains did\n not differ from that of \nother carrier strains.<\/jats:p>","DOI":"10.1017\/s0950268898008930","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:23:42Z","timestamp":1027761822000},"page":"85-94","source":"Crossref","is-referenced-by-count":48,"title":["Dynamics of the meningococcal carrier state and \ncharacteristics of the carrier strains: a longitudinal study \nwithin three cohorts of military recruits"],"prefix":"10.1017","volume":"121","author":[{"given":"J.","family":"ANDERSEN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"BERTHELSEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. BECH","family":"JENSEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"LIND","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[1998,8,1]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268898008930","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T14:51:26Z","timestamp":1554389486000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268898008930\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,8]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1998,8]]}},"alternative-id":["S0950268898008930"],"URL":"https:\/\/doi.org\/10.1017\/s0950268898008930","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,8]]}}}