{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,10]],"date-time":"2024-01-10T03:39:22Z","timestamp":1704857962884},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[1999,4,1]],"date-time":"1999-04-01T00:00:00Z","timestamp":922924800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1999,4]]},"abstract":"<jats:p>A variant of variola virus is described which produces a late polypeptide of 25 kDa instead of \none of 27 kDa and which has an additional endonuclease cleavage site for <jats:italic>Sal<\/jats:italic>I in the viral \nDNA. These markers were shown to be genetically independent and to characterize 14 of the \n48 variola strains which were examined. The variant strains were isolated from smallpox \noutbreaks originating in or from Pakistan between 1961 and 1974 and also from two cases at a \nMission Hospital in Vellore, India in 1964. No variant strains were found among 9 other \nisolates from cases of variola major occurring in other parts of India or in Bangladesh, nor \namong 4 isolates from Indonesia, 15 from Africa or 6 isolates of variola minor.<\/jats:p>","DOI":"10.1017\/s0950268899002150","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T13:23:42Z","timestamp":1027776222000},"page":"287-290","source":"Crossref","is-referenced-by-count":5,"title":["A variant of variola virus, characterized by changes in \npolypeptide and endonuclease profiles"],"prefix":"10.1017","volume":"122","author":[{"given":"K. R.","family":"DUMBELL","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"HARPER","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"BUCHAN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. J.","family":"DOUGLASS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. S.","family":"BEDSON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1999,4,1]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268899002150","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T21:05:22Z","timestamp":1554411922000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268899002150\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,4]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1999,4]]}},"alternative-id":["S0950268899002150"],"URL":"https:\/\/doi.org\/10.1017\/s0950268899002150","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,4]]}}}