{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:58:39Z","timestamp":1791356319021,"version":"4.3.1"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"2","license":[{"start":{"date-parts":[[1999,10,1]],"date-time":"1999-10-01T00:00:00Z","timestamp":938736000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1999,10]]},"abstract":"<jats:p>For many years, invasive meningococcal disease in the Czech Republic occurred sporadically \nand was caused mainly by meningococci of serogroup B. In 1993, when a new clone (ET-15\/37) emerged, the only phenotype found was C:2a:P1.2,5. In 1995, an antigenic variation of \nthe ET-15\/37 clone, B:2a:P1.2,5, occurred. The results of immunological surveys conducted in \n1989 and 1996 were compared. A significantly higher proportion of 1996 sera than those \ncollected in 1989 showed bactericidal antibodies against <jats:italic>N. meningitidis<\/jats:italic> B:2a:P1.2,5 (19\u00b77 <jats:italic>vs.<\/jats:italic> \n5\u00b71%) and <jats:italic>N. meningitidis<\/jats:italic> C:2a:P1.2,5 (15\u00b79 <jats:italic>vs<\/jats:italic>. 7\u00b74%), consistent with increased herd \nimmunity due to the spread of the new clone in the Czech Republic. There were differences in \nthe age distribution of the positive sera.<\/jats:p>","DOI":"10.1017\/s095026889900285x","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T13:23:42Z","timestamp":1027776222000},"page":"193-200","source":"Crossref","is-referenced-by-count":28,"title":["Antimeningococcal herd immunity in the Czech Republic \u2013 \ninfluence of an emerging clone, <i>Neisseria meningitidis<\/i> ET-15\/37"],"prefix":"10.1017","volume":"123","author":[{"given":"P.","family":"KRIZ","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"KRIZ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"SVANDOVA","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"MUSILEK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[1999,10,1]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S095026889900285X","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T20:10:42Z","timestamp":1557432642000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S095026889900285X\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,10]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1999,10]]}},"alternative-id":["S095026889900285X"],"URL":"https:\/\/doi.org\/10.1017\/s095026889900285x","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,10]]}}}