{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:28:14Z","timestamp":1760120894666},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[1999,12,1]],"date-time":"1999-12-01T00:00:00Z","timestamp":944006400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1999,12]]},"abstract":"<jats:p>Protozoa are important enteric pathogens in patients with human immunodeficiency virus \n(HIV) infection. In this study the prevalence of intestinal protozoa in 154 HIV-infected \npatients, with or without diarrhoea, in our region (Apulia, South Italy) was evaluated between \nDecember 1993 and February 1998. In the majority of patients CD4+ T cell count was below \n200\/\u03bcl. The overall prevalence of intestinal protozoa was 43\/154 (27\u00b792%). Twenty-eight \n(43\u00b708%) out of 65 patients with diarrhoea and 15 (16\u00b785%) out of 89 non-diarrhoeic patients \nwere parasitized. In particular, in the group of 65 patients with diarrhoea the following \nprotozoa were identified: <jats:italic>Cryptosporidium parvum<\/jats:italic> in 14 (21\u00b754%), <jats:italic>Blastocystis hominis<\/jats:italic> in 7 \n(10\u00b777%), microsporidia in 6 (9\u00b723%), <jats:italic>Giardia lamblia<\/jats:italic> in 4 (6\u00b715%) and <jats:italic>Isospora belli<\/jats:italic> in 1 \n(1\u00b754%). Three patients were <jats:italic>Cryptosporidium parvum<\/jats:italic>-microsporidia co-infected. In patients \nwithout intestinal symptoms, prevalence was 3\/89 (3\u00b737%) for <jats:italic>Cryptosporidium parvum<\/jats:italic>, 9\/89 \n(10\u00b711%) for <jats:italic>Blastocystis hominis<\/jats:italic>, 1\/89 (1\u00b712%) for microsporidia and 2\/89 (2\u00b725%) for \n<jats:italic>Giardia lamblia<\/jats:italic>. A significant (<jats:italic>P<\/jats:italic>&lt;0\u00b7001) correlation was observed between protozoan infection \nand the presence of diarrhoea. In particular, <jats:italic>Cryptosporidium parvum<\/jats:italic> and microsporidia \ninfections were significantly (<jats:italic>P<\/jats:italic>&lt;0\u00b7001) and <jats:italic>P<\/jats:italic>=0\u00b7046, respectively) associated with diarrhoeal \nillness. Moreover, the majority of cases of cryptosporidiosis were first diagnosed in the periods \nof heaviest rainfall. Therefore, drinking water contamination may be a possible source of \nhuman infection in our area.<\/jats:p>","DOI":"10.1017\/s0950268899003015","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T13:23:42Z","timestamp":1027776222000},"page":"457-461","source":"Crossref","is-referenced-by-count":44,"title":["Intestinal protozoa in HIV-infected patients in Apulia, \nSouth Italy"],"prefix":"10.1017","volume":"123","author":[{"given":"O.","family":"BRANDONISIO","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"MAGGI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. A.","family":"PANARO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"LISI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"ANDRIOLA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"ACQUAFREDDA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"ANGARANO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[1999,12,1]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268899003015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T19:49:36Z","timestamp":1557431376000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268899003015\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,12]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1999,12]]}},"alternative-id":["S0950268899003015"],"URL":"https:\/\/doi.org\/10.1017\/s0950268899003015","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,12]]}}}