{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T10:27:17Z","timestamp":1789986437441,"version":"4.0.1"},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"3","license":[{"start":{"date-parts":[[1999,12,1]],"date-time":"1999-12-01T00:00:00Z","timestamp":944006400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[1999,12]]},"abstract":"<jats:p>Invasive meningococcal disease (IMD) is thought to occur within a few days of pharyngeal \nacquisition of <jats:italic>Neisseria meningitidis<\/jats:italic>. During a longitudinal study of carriage and acquisition \namong 2453 first-year undergraduates we identified a male student from whom <jats:italic>N. lactamica<\/jats:italic> \nwas isolated in October 1997 followed by <jats:italic>N. meningitidis<\/jats:italic> in December 1997. In mid-January \n1998 this student suffered a mild episode of IMD (meningitis) during which <jats:italic>N. meningitidis<\/jats:italic> was \nisolated from his CSF. The meningococcus carried in December 1997 was phenotypically and \ngenotypically indistinguishable from the invading organism, suggesting the possibility that the \norganism may have been carried for 7 weeks prior to the onset of invasive disease. Further \nstudies are needed to assess more accurately the range of asymptomatic carriage prior to \ndisease onset.<\/jats:p>","DOI":"10.1017\/s0950268899003192","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T13:23:42Z","timestamp":1027776222000},"page":"507-509","source":"Crossref","is-referenced-by-count":11,"title":["Seven-week interval between acquisition of a meningococcus \nand the onset of invasive disease. A case report"],"prefix":"10.1017","volume":"123","author":[{"given":"K. R.","family":"NEAL","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. S.","family":"NGUYEN-VAN-TAM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. C. B.","family":"SLACK","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. B.","family":"KACZMARSKI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"WHITE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. A. A.","family":"ALA'ALDEEN","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[1999,12,1]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268899003192","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T19:49:28Z","timestamp":1557431368000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268899003192\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,12]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1999,12]]}},"alternative-id":["S0950268899003192"],"URL":"https:\/\/doi.org\/10.1017\/s0950268899003192","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,12]]}}}