{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:22:49Z","timestamp":1753921369231},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"1","license":[{"start":{"date-parts":[[2000,2,1]],"date-time":"2000-02-01T00:00:00Z","timestamp":949363200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2000,2]]},"abstract":"<jats:p>In this paper we report the distribution of <jats:italic>Salmonella<\/jats:italic> Typhi isolates in Italy and their \nresistance patterns to antibiotics. The data were collected by the Italian SALM\u2013NET \nsurveillance system in a pilot retrospective study of the period 1980\u201396. Data on drug-resistance were available for 82 isolates out of 176 <jats:italic>S<\/jats:italic>. Typhi isolated in Italy. Of these 82 \nisolates, 32 (39%) were resistant or intermediate to 1 or more antibiotics. Eight isolates were \nresistant and 7 intermediate to streptomycin; 4 isolates were resistant to ampicillin alone or in \nassociation with other antibiotics; only 2 strains (1 isolated in Lombardia in 1993 and the \nother 1 in Lazio in 1994) were resistant to chloramphenicol, and 2 (isolated in Sardegna and \nPiemonte in 1995 and 1996, respectively) showed intermediate resistance to chloramphenicol. \nThe strains showing resistance to 3 or more antibiotics were very scarce: 1 (with 5 complete \nresistances) was isolated in Lazio in 1994, and another 1 (with complete resistance to 10 \nantibiotics and intermediate resistance to 2 antibiotics) was isolated in Molise in 1988. In \nconclusion, besides the routine activities to control typhoid fever, an accurate and continuous \nsurveillance is necessary in order to quickly identify multidrug-resistant (MDR) <jats:italic>S<\/jats:italic>. Typhi \nstrains and prevent their spread, even though their level, in our country, is still quite low.<\/jats:p>","DOI":"10.1017\/s0950268899003301","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:23:42Z","timestamp":1027761822000},"page":"17-23","source":"Crossref","is-referenced-by-count":4,"title":["The antibiotic resistance patterns of <i>Salmonella<\/i> Typhi \nisolates in Italy, 1980\u201396"],"prefix":"10.1017","volume":"124","author":[{"given":"G.","family":"SCUDERI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"FANTASIA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"NIGLIO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"ITALIAN SALM\u2013NET WORKING GROUP","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"56","published-online":{"date-parts":[[2000,2,1]]},"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268899003301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,6]],"date-time":"2019-04-06T15:29:54Z","timestamp":1554564594000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268899003301\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,2]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,2]]}},"alternative-id":["S0950268899003301"],"URL":"https:\/\/doi.org\/10.1017\/s0950268899003301","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"value":"0950-2688","type":"print"},{"value":"1469-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,2]]}}}