{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T23:47:46Z","timestamp":1775000866506,"version":"3.50.1"},"reference-count":0,"publisher":"Maximum Academic Press","issue":"4","license":[{"start":{"date-parts":[[2002,1,11]],"date-time":"2002-01-11T00:00:00Z","timestamp":1010707200000},"content-version":"unspecified","delay-in-days":194,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vis Neurosci"],"published-print":{"date-parts":[[2001,7]]},"abstract":"<jats:p>Retinal neurons are generated in overlapping growth spurts \nwith ganglion cell and cone populations peaking sooner than \nrod and bipolar cell numbers. As such the functional development \nof the inner and outer retinal components and elements within \nthese strata (rods <jats:italic>vs.<\/jats:italic> cones) may differ. We considered \nthe postnatal development of the postreceptoral components of \nthe ERG (P2, oscillatory potentials) in the guinea pig. ERGs \nwere also evaluated across albino and pigmented strains in order \nto consider the role that pigmentation has for functional \ndevelopment. Electroretinograms were collected on postnatal \ndays PD1 to PD60 (<jats:italic>n<\/jats:italic> = 4\u20137 per time point). \nThe postreceptoral P2 amplitude and implicit time was extracted \n(digital subtraction of modelled P3 and filtering, \n0.5\u201349 Hz). Intensity\u2013response relationships were \ndescribed using Naka\u2013Rushton functions whose parameters \nwere compared using a nonparametric bootstrap. Oscillatory \npotentials (OPs) were extracted following signal conditioning \nand filtering to remove the <jats:italic>a<\/jats:italic>- and <jats:italic>b<\/jats:italic>-waves \nand were described using a Gabor function. OP response parameters \nwere compared using repeated measures ANOVA. Postreceptoral \nP2 amplitudes mature soon after birth (PD10\u2013PD12). \nOscillatory potentials show a similar postnatal amplitude \ndevelopment (PD10\u2013PD12) but a later maturation in timing \n(PD20) compared with the postreceptoral waveform. All components \n(P3, P2, and OPs) declined at the same relative rate with age \nafter PD12. Albino animals gave larger, faster, and more sensitive \nwaveforms at all ages but showed the same age-related trends \nas did pigmented animals. Early development of inner retinal \nsynapses in guinea pigs may underlie the rapid postnatal maturation \nof their postreceptoral response. These appear to be constrained \nby the development of receptoral responses. All components declined \nat the same rate suggesting either a change in the photoreceptoral \nresponse or changes to ocular impedance with age.<\/jats:p>","DOI":"10.1017\/s0952523801184105","type":"journal-article","created":{"date-parts":[[2002,12,11]],"date-time":"2002-12-11T22:09:24Z","timestamp":1039644564000},"page":"605-613","source":"Crossref","is-referenced-by-count":14,"title":["Development of postreceptoral function in pigmented and albino \nguinea pigs"],"prefix":"10.48130","volume":"18","author":[{"given":"ALGIS J.","family":"VINGRYS","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BANG V.","family":"BUI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27968","published-online":{"date-parts":[[2002,1,11]]},"container-title":["Visual Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0952523801184105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T20:00:53Z","timestamp":1735848053000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0952523801184105\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,7]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2001,7]]}},"alternative-id":["S0952523801184105"],"URL":"https:\/\/doi.org\/10.1017\/s0952523801184105","relation":{},"ISSN":["0952-5238","1469-8714"],"issn-type":[{"value":"0952-5238","type":"print"},{"value":"1469-8714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,7]]}}}