{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:48:08Z","timestamp":1761580088211,"version":"3.32.0"},"reference-count":0,"publisher":"Maximum Academic Press","issue":"1","license":[{"start":{"date-parts":[[2002,6,28]],"date-time":"2002-06-28T00:00:00Z","timestamp":1025222400000},"content-version":"unspecified","delay-in-days":178,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["journals.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Vis Neurosci"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:p>The distribution of preganglionic motoneurons supplying the \nciliary ganglion in the cat was defined both qualitatively and \nquantitatively. These cells were retrogradely labeled directly, \nfollowing injections of wheat germ agglutinin conjugated to \nhorseradish peroxidase (WGA-HRP) into the ciliary ganglion, \nor were transsynaptically labeled following injections of WGA \ninto the vitreous chamber. Almost half of the cells are distributed \nrostral to the oculomotor nucleus, both in and lateral to the \nanteromedian nucleus. Of the remaining preganglionic motoneurons, \nroughly 20% of the total are located dorsal to the oculomotor \nnucleus. Strikingly few of these neurons are actually found \nwithin the Edinger-Westphal nucleus proper. Instead, the majority \nare found in the adjacent supraoculomotor area or along the \nmidline between the two somatic nuclei. An additional population, \nroughly 30% of the total, is located ventral to the oculomotor \nnucleus. This study also provides evidence for a functional \nsubdivision of this preganglionic population. Pupil-related \npreganglionic motoneurons were transsynaptically labeled by \ninjecting WGA into the anterior chamber, while lens-related \npreganglionic motoneurons were transsynaptically labeled by \ninjecting WGA into the ciliary muscle. The results suggest that \nthe pupil-related preganglionic motoneurons, that is, those \ncontrolling the iris sphincter pupillae muscle, are located \nrostrally, in and lateral to the anteromedian nucleus. In contrast, \nlens-related preganglionic motoneurons, that is, those controlling \nthe ciliary muscle are particularly prevalent caudally, both \ndorsal and ventral to the oculomotor nucleus. Thus, the cat \nintraocular muscle preganglionic innervation is spatially organized \nwith respect to function, despite the dispersed nature of its \ndistribution.<\/jats:p>","DOI":"10.1017\/s0952523801191029","type":"journal-article","created":{"date-parts":[[2002,12,11]],"date-time":"2002-12-11T22:10:20Z","timestamp":1039644620000},"page":"15-29","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":26,"title":["The pupillary and ciliary components of the cat Edinger-Westphal \nnucleus: A transsynaptic transport investigation"],"prefix":"10.48130","volume":"19","author":[{"given":"JONATHAN T.","family":"ERICHSEN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PAUL J.","family":"MAY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27968","published-online":{"date-parts":[[2002,6,28]]},"container-title":["Visual Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0952523801191029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T20:01:07Z","timestamp":1735848067000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0952523801191029\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2002,1]]}},"alternative-id":["S0952523801191029"],"URL":"https:\/\/doi.org\/10.1017\/s0952523801191029","relation":{},"ISSN":["0952-5238","1469-8714"],"issn-type":[{"type":"print","value":"0952-5238"},{"type":"electronic","value":"1469-8714"}],"subject":[],"published":{"date-parts":[[2002,1]]},"assertion":[{"value":"Cambridge University Press 2011","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}