{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:16:59Z","timestamp":1785428219534,"version":"3.56.0"},"reference-count":62,"publisher":"Cambridge University Press (CUP)","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"unspecified","delay-in-days":113,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Nutr. Res. Rev."],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Neuromuscular disorders (NMDs) are a heterogeneous group of conditions characterised by progressive muscle weakness, motor impairment, and risk of malnutrition, affecting the quality of life (QoL) of patients. While pharmacological treatments are essential for the management of symptoms, the role of diet, nutrition, and other lifestyle factors remains underexplored. This narrative systematic review, performed on PubMed, Web of Science, and Scopus following PRISMA guidelines, aimed to investigate the relationship between lifestyle, the progression of NMDs, and the QoL. A total of 30 studies (\n                    <jats:italic>n<\/jats:italic>\n                    = 5055 patients) met inclusion criteria. According to our search strategy, the most representative lifestyle factors were diet (70%), physical activity (53.3%), and emotional perception and care (36.7%); seven papers (23.3%) evaluated three or more lifestyle aspects. Overall, both quantitative and qualitative deficiencies emerged: calories, proteins, lipids, and fibres, as well as vitamin C, vitamin E, zinc, selenium, and calcium, were lower than recommended. A reduced consumption of fruits, vegetables, legumes, nuts, and seeds, replaced by ultra-processed foods, was detected. Diets optimised for calorie and nutrients intake, rich in anti-inflammatory foods, have shown benefits both in mitigating oxidative stress and muscle degeneration. Regarding other aspects of lifestyle, although physical activity was associated with improved motor performance and QoL, adherence was low, particularly among females. Negative emotional status emerged as a critical factor influencing patients\u2019 overall well-being. Even in the most complex neuromuscular disease settings, addressing nutrition and dietary habits, in the context of lifestyle, could support patients and their families throughout the disease course and improve their QoL.\n                  <\/jats:p>","DOI":"10.1017\/s0954422426100420","type":"journal-article","created":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T08:36:37Z","timestamp":1777019797000},"update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":0,"title":["Diet and nutrition in patients with neuromuscular disorders, as lifestyle factors affecting clinical parameters and quality of life: a narrative systematic review"],"prefix":"10.1017","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0464-8624","authenticated-orcid":false,"given":"Silvia","family":"Marconi","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02q2d2610","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Brescia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Gilberti","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02q2d2610","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Brescia"},{"name":"NeMO Clinical Center for Neuromuscular Diseases"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Zanini","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02q2d2610","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Brescia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Marullo","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02q2d2610","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Brescia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Montani","sequence":"additional","affiliation":[{"name":"ASST Spedali Civili di Brescia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Risi","sequence":"additional","affiliation":[{"name":"NeMO Clinical Center for Neuromuscular Diseases"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Padovani","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02q2d2610","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Brescia"},{"name":"ASST Spedali Civili di Brescia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Castellano","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02q2d2610","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Brescia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Filosto","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02q2d2610","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Brescia"},{"name":"NeMO Clinical Center for Neuromuscular Diseases"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"S0954422426100420_ref39","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-020-01416-6"},{"key":"S0954422426100420_ref48","unstructured":"48. World Health Organization (WHO). WHO guidelines on physical activity and sedentary behaviour. https:\/\/www.who.int\/publications\/i\/item\/9789240015128 (accessed February 2025)."},{"key":"S0954422426100420_ref16","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-023-07150-x"},{"key":"S0954422426100420_ref15","first-page":"1","article-title":"Strength training and aerobic exercise training for muscle disease","volume":"12","author":"Voet","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"S0954422426100420_ref34","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2020.05.014"},{"key":"S0954422426100420_ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2021.07.008"},{"key":"S0954422426100420_ref8","doi-asserted-by":"publisher","DOI":"10.5409\/wjcp.v12.i4.197"},{"key":"S0954422426100420_ref13","first-page":"29657","article-title":"A multidisciplinary approach and current perspective of nonalcoholic fatty liver disease: a systematic review","volume":"14","author":"Zaman","year":"2022","journal-title":"Cureus"},{"key":"S0954422426100420_ref21","doi-asserted-by":"publisher","DOI":"10.3233\/JND-230027"},{"key":"S0954422426100420_ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s40120-022-00408-x"},{"key":"S0954422426100420_ref49","doi-asserted-by":"publisher","DOI":"10.3233\/JND-140045"},{"key":"S0954422426100420_ref59","doi-asserted-by":"publisher","DOI":"10.3390\/nu13010196"},{"key":"S0954422426100420_ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2021.06.008"},{"key":"S0954422426100420_ref44","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2024.04.001"},{"key":"S0954422426100420_ref1","doi-asserted-by":"publisher","DOI":"10.3390\/nu9060594"},{"key":"S0954422426100420_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2021.01.013"},{"key":"S0954422426100420_ref9","doi-asserted-by":"publisher","DOI":"10.3148\/cjdpr-2021-003"},{"key":"S0954422426100420_ref50","doi-asserted-by":"publisher","DOI":"10.3390\/nu16132143"},{"key":"S0954422426100420_ref62","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2025.112990"},{"key":"S0954422426100420_ref6","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.12987"},{"key":"S0954422426100420_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2023.115664"},{"key":"S0954422426100420_ref38","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare12090937"},{"key":"S0954422426100420_ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2017.04.019"},{"key":"S0954422426100420_ref52","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2018.08.002"},{"key":"S0954422426100420_ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2021.05.007"},{"key":"S0954422426100420_ref42","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2018.1528305"},{"key":"S0954422426100420_ref2","first-page":"1","article-title":"Interventions for promoting physical activity in people with neuromuscular disease","volume":"5","author":"Jones","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"key":"S0954422426100420_ref60","doi-asserted-by":"publisher","DOI":"10.3390\/nu8120747"},{"key":"S0954422426100420_ref27","doi-asserted-by":"publisher","DOI":"10.3233\/JND-220796"},{"key":"S0954422426100420_ref61","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2020.00558"},{"key":"S0954422426100420_ref43","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2021.2008528"},{"key":"S0954422426100420_ref17","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17238758"},{"key":"S0954422426100420_ref24","doi-asserted-by":"publisher","DOI":"10.1002\/mus.28065"},{"key":"S0954422426100420_ref23","doi-asserted-by":"publisher","DOI":"10.3233\/JND-210693"},{"key":"S0954422426100420_ref30","first-page":"417","article-title":"Predictors to health promoting behaviors among patients with myasthenia gravis: health belief model approach","volume":"30","author":"Elkady","year":"2023","journal-title":"J Popul Ther Clin Pharmacol"},{"key":"S0954422426100420_ref35","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25661"},{"key":"S0954422426100420_ref18","doi-asserted-by":"publisher","DOI":"10.2174\/0929867328666210504113445"},{"key":"S0954422426100420_ref47","unstructured":"47. United States Department of Agriculture. Nutrient recommendations and databases. https:\/\/www.nal.usda.gov (accessed February 2025)."},{"key":"S0954422426100420_ref41","doi-asserted-by":"publisher","DOI":"10.1002\/jimd.12741"},{"key":"S0954422426100420_ref55","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2025.105783"},{"key":"S0954422426100420_ref51","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-023-11658-6"},{"key":"S0954422426100420_ref33","doi-asserted-by":"publisher","DOI":"10.1080\/1028415X.2018.1466459"},{"key":"S0954422426100420_ref10","doi-asserted-by":"publisher","DOI":"10.1111\/apa.16649"},{"key":"S0954422426100420_ref29","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2021-328331"},{"key":"S0954422426100420_ref58","doi-asserted-by":"publisher","DOI":"10.1039\/D4FO03002H"},{"key":"S0954422426100420_ref19","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.1243513"},{"key":"S0954422426100420_ref28","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-020-01549-z"},{"key":"S0954422426100420_ref5","doi-asserted-by":"publisher","DOI":"10.3390\/nu15071673"},{"key":"S0954422426100420_ref46","unstructured":"46. 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Published by Cambridge University Press on behalf of The Nutrition Society","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https:\/\/creativecommons.org\/licenses\/by\/4.0\/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}],"article-number":"e21"}}