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Using data from the NICHD Study of Early Child Care (<jats:italic>n<\/jats:italic> = 1,364 families), we examined mother\u2013child relationships, other aspects of family context, and child characteristics as predictors of anxiety in preadolescence. Latent growth curve analyses revealed that children who were more anxious at the beginning of middle childhood had been more behaviorally inhibited as preschoolers, and in middle childhood lived in families who experienced more negative life events and had mothers who were more anxious. Children who became more anxious across middle childhood were less behaviorally inhibited as preschoolers and in middle childhood perceived less security in their attachments to their mothers, experienced more negative life events, and had mothers who were more anxious. The findings illustrate the need to include a broad set of risk factors in etiological models of anxiety. In addition, the evidence for cumulative effects suggests several possible points of intervention with anxious children and their parents.<\/jats:p>","DOI":"10.1017\/s0954579411000228","type":"journal-article","created":{"date-parts":[[2011,4,18]],"date-time":"2011-04-18T05:01:51Z","timestamp":1303102911000},"page":"593-604","source":"Crossref","is-referenced-by-count":29,"title":["Mother\u2013child relationships, family context, and child characteristics as predictors of anxiety symptoms in middle childhood"],"prefix":"10.1017","volume":"23","author":[{"given":"Kathryn A.","family":"Kerns","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon","family":"Siener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura 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