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Children (<jats:italic>M<\/jats:italic>age = 11.26,<jats:italic>SD<\/jats:italic>= 1.65), including 156 maltreated and 145 nonmaltreated children from comparable low socioeconomic backgrounds, provided DNA samples and self-reports of relational peer victimization, overt peer victimization, and depressive symptoms. Path analysis showed that relational and overt victimization mediated the association between child maltreatment and depressive symptoms. Bootstrapping procedures were used to test moderated mediation and demonstrated that genotype moderated the indirect effects of relational and overt victimization on child depressive symptoms, such that victimized children with the long\/long variation were at an increased risk for depressive symptoms compared to victimized children carrying a short allele. 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