{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T21:06:30Z","timestamp":1788210390499,"version":"build-2803163510"},"reference-count":59,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2017,12,7]],"date-time":"2017-12-07T00:00:00Z","timestamp":1512604800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dev Psychopathol"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Struggles managing conflict and hostility in adolescent social relationships were examined as long-term predictors of immune-mediated inflammation in adulthood that has been linked to long-term health outcomes. Circulating levels of interleukin-6 (IL-6), a marker of immune system dysfunction when chronically elevated, were assessed at age 28 in a community sample of 127 individuals followed via multiple methods and reporters from ages 13 to 28. Adult serum IL-6 levels were predicted across periods as long as 15 years by adolescents\u2019 inability to defuse peer aggression and poor peer-rated conflict resolution skills, and by independently observed romantic partner hostility in late adolescence. Adult relationship difficulties also predicted higher IL-6 levels but did not mediate predictions from adolescent-era conflict struggles. Predictions were also not mediated by adult trait hostility or aggressive behavior, suggesting the unique role of struggles with conflict and hostility from others during adolescence. The implications for understanding the import of adolescent peer relationships for life span physical health outcomes are considered.<\/jats:p>","DOI":"10.1017\/s0954579417001754","type":"journal-article","created":{"date-parts":[[2017,12,7]],"date-time":"2017-12-07T09:07:56Z","timestamp":1512637676000},"page":"1435-1445","source":"Crossref","is-referenced-by-count":22,"title":["The body remembers: Adolescent conflict struggles predict adult interleukin-6 levels"],"prefix":"10.1017","volume":"30","author":[{"given":"Joseph P.","family":"Allen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily L.","family":"Loeb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph S.","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel K.","family":"Narr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bert N.","family":"Uchino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2017,12,7]]},"reference":[{"key":"S0954579417001754_ref36","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00041.2006"},{"key":"S0954579417001754_ref47","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2013.1100"},{"key":"S0954579417001754_ref32","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2011.10.005"},{"key":"S0954579417001754_ref22","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0b013e3181921b1f"},{"key":"S0954579417001754_ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2012.12.010"},{"key":"S0954579417001754_ref28","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3153"},{"key":"S0954579417001754_ref48","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2005.03.009"},{"key":"S0954579417001754_ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-6494.2004.00295.x"},{"key":"S0954579417001754_ref14","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1002\/9780471726746.ch11","volume-title":"Handbook of adolescent psychology","author":"Collins","year":"2004"},{"key":"S0954579417001754_ref31","article-title":"Perceptions of parental secure base support in African American adolescents and young adults","author":"Jones","year":"2016","journal-title":"Journal of Social and Personal Relationships"},{"key":"S0954579417001754_ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2016.02.008"},{"key":"S0954579417001754_ref50","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0b013e3181e9c16f"},{"key":"S0954579417001754_ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2009.12.009"},{"key":"S0954579417001754_ref41a","doi-asserted-by":"publisher","DOI":"10.1037\/0012-1649.29.4.611"},{"key":"S0954579417001754_ref2","volume-title":"The autonomy and relatedness coding system","author":"Allen","year":"2000"},{"key":"S0954579417001754_ref3","volume-title":"Autonomy and relatedness coding manual for adolescent-romantic partner dyads","author":"Allen","year":"2005"},{"key":"S0954579417001754_ref10","doi-asserted-by":"publisher","DOI":"10.1037\/h0046900"},{"key":"S0954579417001754_ref49","doi-asserted-by":"publisher","DOI":"10.1037\/a0035302"},{"key":"S0954579417001754_ref12","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.80.1.136"},{"key":"S0954579417001754_ref46","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1002\/dev.20437","article-title":"Adolescence: A central event in shaping stress reactivity","volume":"52","author":"Romeo","year":"2010","journal-title":"Developmental Psychobiology"},{"key":"S0954579417001754_ref27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000316"},{"key":"S0954579417001754_ref11","unstructured":"Centers for Disease Control and Prevention. (2017). Four domains of chronic disease prevention. Retrieved from https:\/\/www.cdc.gov\/chronicdisease\/resources\/publications\/four-domains.htm"},{"key":"S0954579417001754_ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jrp.2005.08.007"},{"key":"S0954579417001754_ref55","doi-asserted-by":"publisher","DOI":"10.1007\/s12529-010-9082-0"},{"key":"S0954579417001754_ref21","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.46.6.1448"},{"key":"S0954579417001754_ref40","doi-asserted-by":"publisher","DOI":"10.1177\/2167702612455743"},{"key":"S0954579417001754_ref15","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000158483.13093.9D"},{"key":"S0954579417001754_ref44","doi-asserted-by":"publisher","DOI":"10.1177\/0165025411406860"},{"key":"S0954579417001754_ref33","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.62.12.1377"},{"key":"S0954579417001754_ref1","doi-asserted-by":"publisher","DOI":"10.1177\/0963721412471347"},{"key":"S0954579417001754_ref43","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-006-9082-1"},{"key":"S0954579417001754_ref34","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.537878"},{"key":"S0954579417001754_ref51","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-6494.2004.00296.x"},{"key":"S0954579417001754_ref7","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/31.2.285"},{"key":"S0954579417001754_ref54","doi-asserted-by":"publisher","DOI":"10.1037\/0012-1649.43.6.1531"},{"key":"S0954579417001754_ref37","doi-asserted-by":"publisher","DOI":"10.1177\/0956797610370161"},{"key":"S0954579417001754_ref42","doi-asserted-by":"publisher","DOI":"10.1111\/cdev.12313"},{"key":"S0954579417001754_ref29","volume-title":"Accelerating progress in obesity prevention: Solving the weight of the nation","year":"2012"},{"key":"S0954579417001754_ref9","doi-asserted-by":"publisher","DOI":"10.1177\/0956797615626703"},{"key":"S0954579417001754_ref14a","volume-title":"Manual for the revised Beck Depression Inventory","author":"Beck","year":"1987"},{"key":"S0954579417001754_ref8","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579401003042"},{"key":"S0954579417001754_ref23","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3446-12.2013"},{"key":"S0954579417001754_ref52","first-page":"993","volume-title":"The use of psychological testing for treatment planning and outcomes assessment","author":"Spielberger","year":"1999"},{"key":"S0954579417001754_ref4","doi-asserted-by":"publisher","DOI":"10.1177\/0956797615594118"},{"key":"S0954579417001754_ref39","doi-asserted-by":"publisher","DOI":"10.1037\/a0024768"},{"key":"S0954579417001754_ref30","doi-asserted-by":"publisher","DOI":"10.1177\/0956797615595962"},{"key":"S0954579417001754_ref5","first-page":"243","volume-title":"Advanced structural modeling: Issues and techniques","author":"Arbuckle","year":"1996"},{"key":"S0954579417001754_ref26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1999.tb08107.x"},{"key":"S0954579417001754_ref41","doi-asserted-by":"publisher","DOI":"10.1037\/0033-295X.84.3.231"},{"key":"S0954579417001754_ref38","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0902971106"},{"key":"S0954579417001754_ref20","doi-asserted-by":"publisher","DOI":"10.1177\/0963721414535603"},{"key":"S0954579417001754_ref13","first-page":"127","article-title":"Developing criteria for establishing interrater reliability of specific items: Applications to assessment of adaptive behavior","volume":"86","author":"Cicchetti","year":"1981","journal-title":"American Journal of Mental Deficiency"},{"key":"S0954579417001754_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2010.11.007"},{"key":"S0954579417001754_ref18","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579415000334"},{"key":"S0954579417001754_ref56","doi-asserted-by":"publisher","DOI":"10.1177\/0265407509105521"},{"key":"S0954579417001754_ref35","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/54.9.M434"},{"key":"S0954579417001754_ref57","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1511085112"},{"key":"S0954579417001754_ref45","volume-title":"The Achenbach System of Empirically Based Assessment (ASEBA) for ages 18 to 90 years","author":"Rescorla","year":"2004"},{"key":"S0954579417001754_ref53","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2004.12.005"}],"container-title":["Development and Psychopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0954579417001754","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T14:16:35Z","timestamp":1719670595000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0954579417001754\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,7]]},"references-count":59,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["S0954579417001754"],"URL":"https:\/\/doi.org\/10.1017\/s0954579417001754","relation":{},"ISSN":["0954-5794","1469-2198"],"issn-type":[{"value":"0954-5794","type":"print"},{"value":"1469-2198","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,7]]}}}